Evidence map›Paper›PMID 34376903›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2018

Multi-atlas segmentation of the hydrocephalus brain using an adaptive ventricle atlas.

Muhan Shao, Aaron Carass, Xiang Li, Blake E Dewey, Ari M Blitz, Jerry L Prince, Lotta M Ellingsen

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Investigation of probability maps in deep-learning-based brain ventricle parcellation.Proceedings of SPIE--the International Society for Optical Engineering · 2023
    Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Muhan ShaoDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218.
Aaron CarassDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218.
Xiang LiDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218.
Blake E DeweyDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218.
Ari M BlitzDepartment of Radiology and Radiological Science, The Johns Hopkins University, Baltimore, MD 21287.
Jerry L PrinceDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218.
Lotta M EllingsenDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218.
Johns Hopkins University · USUniversity of Iceland · IS

Funding

Ventricle segmentation and labeling to characterize normal pressure hydrocephalusR21NS096497 · NINDS · JOHNS HOPKINS UNIVERSITY · PI PRINCE, JERRY L · 2016 to 2017
$426k
NINDS NIH HHS R21 NS096497
6 · The paper itself

Abstract

Normal pressure hydrocephalus (NPH) is a brain disorder caused by disruption of the flow of cerebrospinal fluid (CSF). The dementia-like symptoms of NPH are often mistakenly attributed to Alzheimer's disease. However, if correctly diagnosed, NPH patients can potentially be treated and their symptoms reversed through surgery. Observing the dilated ventricles through magnetic resonance imaging (MRI) is one element in diagnosing NPH. Diagnostic accuracy therefore benefits from accurate, automatic parcellation of the ventricular system into its sub-compartments. We present an improvement to a whole brain segmentation approach designed for subjects with enlarged and deformed ventricles. Our method incorporates an adaptive ventricle atlas from an NPH-atlas-based segmentation as a prior and uses a more robust relaxation scheme for the multi-atlas label fusion approach that accurately labels the four sub-compartments of the ventricular system. We validated our method on NPH patients, demonstrating improvement over state-of-the-art segmentation techniques.

Indexed as

enlarged brain ventricleshydrocephalusMRIsegmentation

Identifiers

PMID34376903
PMCPMC8351536
OpenAlexW2791881557

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.