Evidence map›Paper›PMID 34376765›Full record

ArticleScientific reports2021

Hyperspectral image processing for the identification and quantification of lentiviral particles in fluid samples.

Emilio Gomez-Gonzalez, Beatriz Fernandez-Muñoz, Alejandro Barriga-Rivera, Jose Manuel Navas-Garcia, Isabel Fernandez-Lizaranzu, Francisco Javier Munoz-Gonzalez, Ruben Parrilla-Giraldez, Desiree Requena-Lancharro, Manuel Guerrero-Claro, Pedro Gil-Gamboa and 17 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Polarimetric imaging for the detection of synthetic models of SARS-CoV-2: A proof of concept.Journal of quantitative spectroscopy & radiative transfer · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 10 institutions in 2 countries.

Emilio Gomez-GonzalezDepartment of Applied Physics III, School of Engineering, Universidad de Sevilla, Camino de los Descubrimientos s/n, 41092, Sevilla, Spain. egomez@us.es.
Beatriz Fernandez-MuñozUnidad de Producción y Reprogramación Celular (UPRC), Red Andaluza de Diseño y Traslación de Terapias Avanzadas, 41092, Sevilla, Spain.
Alejandro Barriga-RiveraDepartment of Applied Physics III, School of Engineering, Universidad de Sevilla, Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.
Jose Manuel Navas-GarciaEOD-CBRN Group, Spanish National Police, 41011, Sevilla, Spain.
Isabel Fernandez-LizaranzuDepartment of Applied Physics III, School of Engineering, Universidad de Sevilla, Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.
Francisco Javier Munoz-GonzalezDepartment of Applied Physics III, School of Engineering, Universidad de Sevilla, Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.
Ruben Parrilla-GiraldezTechnology and Innovation Centre, Universidad de Sevilla, 41012, Sevilla, Spain.
Desiree Requena-LancharroDepartment of Applied Physics III, School of Engineering, Universidad de Sevilla, Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.
Manuel Guerrero-ClaroDepartment of Applied Physics III, School of Engineering, Universidad de Sevilla, Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.
Pedro Gil-GamboaDepartment of Applied Physics III, School of Engineering, Universidad de Sevilla, Camino de los Descubrimientos s/n, 41092, Sevilla, Spain.
Cristina Rosell-ValleInstitute of Biomedicine of Seville, 41013, Sevilla, Spain.
Carmen Gomez-GonzalezService of Intensive Care, University Hospital 'Virgen del Rocio', 41013, Sevilla, Spain.
Maria Jose Mayorga-BuizaInstitute of Biomedicine of Seville, 41013, Sevilla, Spain.
Maria Martin-LopezInstitute of Biomedicine of Seville, 41013, Sevilla, Spain.
Olga MuñozInstituto de Astrofísica de Andalucía, CSIC, 18008, Granada, Spain.
Juan Carlos Gomez MartinInstituto de Astrofísica de Andalucía, CSIC, 18008, Granada, Spain.
Maria Isabel Relimpio LopezDepartment of Ophthalmology, University Hospital 'Virgen Macarena', 41009, Sevilla, Spain.
Jesus Aceituno-CastroInstituto de Astrofísica de Andalucía, CSIC, 18008, Granada, Spain.
Manuel A Perales-EsteveDepartment of Electronic Engineering, School of Engineering, Universidad de Sevilla, 41092, Sevilla, Spain.
Antonio Puppo-MorenoService of Intensive Care, University Hospital 'Virgen del Rocio', 41013, Sevilla, Spain.
Francisco Jose Garcia CozarDepartment of Biomedicine, Biotechnology and Public Health, University of Cadiz, 11003, Cadiz, Spain.
Lucia Olvera-CollantesInstituto de Investigación E Innovación Biomedica de Cádiz (INIBICA), 11009, Cadiz, Spain.
Silvia de Los Santos-TrigoCorporación Tecnológica de Andalucía, 41092, Sevilla, Spain.
Emilia GomezJoint Research Centre, European Commission, 41092, Sevilla, Spain.
Rosario Sanchez PernauteUnidad de Producción y Reprogramación Celular (UPRC), Red Andaluza de Diseño y Traslación de Terapias Avanzadas, 41092, Sevilla, Spain.
Javier Padillo-RuizInstitute of Biomedicine of Seville, 41013, Sevilla, Spain.
Javier Marquez-RivasInstitute of Biomedicine of Seville, 41013, Sevilla, Spain.
Universidad de Sevilla · ESInstituto de Biomedicina de Sevilla · ESHospital Universitario Virgen del Rocío · ESInstituto de Astrofísica de Andalucía · ESBiomedical Research and Innovation Institute of Cadiz · ESInstituto de Salud Carlos III · ESJoint Research Center · ESTechnological Corporation of Andalusia · ESUniversidad de Cádiz · ESUniversity of Sydney · AU

Funding

Instituto de Salud Carlos III COV20-00080Instituto de Salud Carlos III COV20-00173Ministerio de Ciencia e Innovación EQC2019-006240-PSpanish National Research Agency RTI2018-094465-J
6 · The paper itself

Abstract

Optical spectroscopic techniques have been commonly used to detect the presence of biofilm-forming pathogens (bacteria and fungi) in the agro-food industry. Recently, near-infrared (NIR) spectroscopy revealed that it is also possible to detect the presence of viruses in animal and vegetal tissues. Here we report a platform based on visible and NIR (VNIR) hyperspectral imaging for non-contact, reagent free detection and quantification of laboratory-engineered viral particles in fluid samples (liquid droplets and dry residue) using both partial least square-discriminant analysis and artificial feed-forward neural networks. The detection was successfully achieved in preparations of phosphate buffered solution and artificial saliva, with an equivalent pixel volume of 4 nL and lowest concentration of 800 TU·[Formula: see text]L

Indexed as

HEK293 CellsHumansImage Processing, Computer-AssistedLentivirusLentivirus InfectionsMolecular Diagnostic TechniquesPoint-of-Care SystemsSalivaSensitivity and SpecificitySpectroscopy, Near-Infrared

Identifiers

PMID34376765
PMCPMC8355230
OpenAlexW3192645423

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.