Evidence map›Paper›PMID 34376749›Full record

Observational studyScientific reports2021

Talaromyces marneffei and nontuberculous mycobacteria co-infection in HIV-negative patients.

Ye Qiu, Jie Huang, Yu Li, Wen Zeng, Mianluan Pan, Jiemei Cen, Hui Zhang, Xuejiao Sun, Dongming Qu, Jianquan Zhang

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Clinical features ofFrontiers in medicine · 2025
    Article
  8. Th1 cell immune response inMicrobiology spectrum · 2024
    Article
  9. Anticytokine Autoantibodies in Infectious Diseases: A Practical Overview.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Ye Qiu *Department of Respiratory and Critical Medicine, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518000, Guangdong, China.
Jie Huang *Department of Tuberculosis Ward, Nanning Forth People's Hospital, Nanning, 530021, Guangxi, China.
Yu Li *Department of Respiratory and Critical Medicine, Yiyang Central Hospital, Yiyang, 413000, Hunan, China.
Wen ZengDepartment of Respiratory and Critical Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Mianluan PanDepartment of Respiratory and Critical Medicine, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518000, Guangdong, China.
Jiemei CenDepartment of Respiratory and Critical Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Hui ZhangDepartment of Respiratory and Critical Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Xuejiao SunDepartment of Respiratory and Critical Medicine, Liuzhou First People's Hospital, Liuzhou, 545000, Guangxi, China.
Dongming QuDepartment of Respiratory and Critical Medicine, Nan Xishan Hospital of Guangxi Zhuang Autonomous Region, Guilin, 541000, Guangxi, China.
Jianquan ZhangDepartment of Respiratory and Critical Medicine, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518000, Guangdong, China. jqzhang2002@126.com.
First Affiliated Hospital of GuangXi Medical University · CNGuangxi Medical University · CNEighth Affiliated Hospital of Sun Yat-sen UniversityLiuzhou General Hospital · CNNanxi Mountain Hospital · CNSun Yat-sen University · CNThe Second Nanning People's Hospital · CNYichang Central People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To describe the clinical features and the risk factors for nontuberculous mycobacteria (NTM) and Talaromyces marneffei (TM) co-infections in HIV-negative patients. A multicenter retrospective study in 13 hospitals, and a systematic literature review were performed of original articles published in English related to TM/NTM co-infections. HIV-negative patients with TM and NTM co-infections comprised Group 1; TM-only infection Group 2; NTM-only infection Group 3; and healthy volunteers Group 4. Univariate logistic analysis was used to estimate the potential risk factors of TM/NTM co-infections. A total of 22 cases of TM and NTM co-infections were enrolled. Of these, 17 patients (77.3%) had a missed diagnosis of one of the TM or NTM pathogens. The anti-IFN-γ autoantibodies (AIGAs) titer, white blood cell (WBC), neutrophil counts (N), erythrocyte sedimentation rate (ESR), C reactive protein (CRP), globulin, and immunoglobulin G (IgG) levels of Group 1 were higher than those of the other groups, whereas the levels of CD4

Indexed as

HIV InfectionsAdultAgedCase-Control StudiesChinaCoinfectionCytokinesFemaleFollow-Up StudiesHumansMaleMiddle AgedMycobacterium Infections, NontuberculousNontuberculous MycobacteriaPrognosisRetrospective StudiesCytokines

Identifiers

PMID34376749
PMCPMC8355300
OpenAlexW3189478141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.