Evidence map›Paper›PMID 34376580›Full record

ArticleMolecular cancer therapeutics2021

KIT

Sudeep Banerjee, Hyunho Yoon, Stephanie Ting, Chih-Min Tang, Mayra Yebra, Alexander T Wenzel, Huwate Yeerna, Jill P Mesirov, Robert J Wechsler-Reya, Pablo Tamayo and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Promising predictive molecular biomarkers for cervical cancer (Review).International journal of molecular medicine · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Sudeep Banerjee *Department of Surgery, Division of Surgical Oncology, University of California, San Diego, California.
Hyunho Yoon *Department of Surgery, Division of Surgical Oncology, University of California, San Diego, California.
Stephanie TingMoores Cancer Center, University of California, San Diego, California.ORCID 0000-0002-4060-0102
Chih-Min TangDepartment of Surgery, Division of Surgical Oncology, University of California, San Diego, California.
Mayra YebraDepartment of Surgery, Division of Surgical Oncology, University of California, San Diego, California.
Alexander T WenzelMoores Cancer Center, University of California, San Diego, California.ORCID 0000-0002-2056-2938
Huwate YeernaMoores Cancer Center, University of California, San Diego, California.
Jill P MesirovMoores Cancer Center, University of California, San Diego, California.
Robert J Wechsler-ReyaSanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Pablo TamayoMoores Cancer Center, University of California, San Diego, California.
Jason K SicklickDepartment of Surgery, Division of Surgical Oncology, University of California, San Diego, California. jsicklick@health.ucsd.edu.
University of California System · USDiscovery Institute · USUniversity of California, Los Angeles · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Nodora · 1985 to 2026
$124.9M
Using Networks to Seed Hierarchical Whole-cell Models of CancerU54CA209891 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KROGAN, NEVAN J · 2017 to 2021
$10.9M
UCSD Cancer Center Training Program in Drug DevelopmentT32CA121938 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Michael Bouvet, Dwayne G. Stupack · 2006 to 2026
$10.3M
San Diego Biomedical Informatics Education & Research (SABER)T15LM011271 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAMIM NEMATI · 2012 to 2026
$9.7M
Supporting Integrative Genomic Analysis Users with GenePatternR01GM074024 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MESIROV, JILL P. · 2005 to 2019
$6.6M
A Rational Systematic Approach to Find Combinations of Pharmacologic and Immune Therapies that Target Identifiable Oncogenic StatesU01CA217885 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI COHEN, EZRA, KAUFMAN, DAN S. · 2017 to 2021
$5.1M
Stimulating Neo-Antigen Specific T Cell Responses in Head and Neck CancersU01DE028227 · NIDCR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI GUTKIND, JORGE SILVIO, RAO, ANJANA · 2018 to 2022
$4.6M
GenePattern and GenePattern Notebook: Integrative 'Omic Analysis for Cancer ResearchU24CA248457 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MESIROV, JILL P., TAMAYO, PABLO · 2020 to 2024
$4.6M
Next-generation Functional Genetic Screening of Un-screenable TraitsR01HG009285 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALI, PRASHANT, TAMAYO, PABLO · 2017 to 2020
$4.2M
Supporting and evolving Gene Set Enrichment Analysis and the Molecular Signatures Database for cancer researchU24CA220341 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MESIROV, JILL P., TAMAYO, PABLO · 2018 to 2022
$3.4M
GenePattern Notebooks for Cancer ResearchU24CA194107 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MESIROV, JILL P. · 2015 to 2019
$2.8M
Targeting the EGFR-PI3K/mTOR Signaling Circuitry: A Network-Based Approach for Oral Cancer Precision TherapyR01DE026870 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GUTKIND, JORGE SILVIO · 2018 to 2022
$2.3M
FDA HHS R01 FD006334NCI NIH HHS K08 CA168999NCI NIH HHS P30 CA023100NCI NIH HHS R01 CA154480NCI NIH HHS R01 CA226803NCI NIH HHS T32 CA121938NCI NIH HHS U01 CA217885NCI NIH HHS U24 CA194107NCI NIH HHS U24 CA220341NCI NIH HHS U24 CA248457NCI NIH HHS U54 CA209891NHGRI NIH HHS R01 HG009285NIDCR NIH HHS R01 DE026870NIDCR NIH HHS U01 DE028227NIGMS NIH HHS R01 GM074024NLM NIH HHS T15 LM011271
6 · The paper itself

Abstract

Gastrointestinal stromal tumor (GIST) is commonly driven by oncogenic

Indexed as

Drug Resistance, NeoplasmAnimalsAntineoplastic AgentsApoptosisBiomarkers, TumorCell ProliferationGastrointestinal NeoplasmsGastrointestinal Stromal TumorsGene Expression Regulation, NeoplasticHumansImatinib MesylateMaleMiceMice, NudeNeoplastic Stem CellsProto-Oncogene Proteins c-kitAntineoplastic AgentsBiomarkers, TumorImatinib MesylateKIT protein, humanProto-Oncogene Proteins c-kit

Identifiers

PMID34376580
PMCPMC8492542
OpenAlexW3193151996

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.