Evidence map›Paper›PMID 34376573›Full record

Observational studyOpen heart2021

Echocardiography in suspected coronavirus infection: indications, limitations and impact on clinical management.

Megan M Sheehan, Yoshihito Saijo, Zoran B Popovic, Michael D Faulx

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Megan M SheehanEC-10, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Yoshihito SaijoCardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.ORCID 0000-0002-1621-0200
Zoran B PopovicCardiovascular Medicine, Cleveland Clinic Main Campus Hospital, Cleveland, Ohio, USA.
Michael D FaulxCardiovascular Medicine, Cleveland Clinic Main Campus Hospital, Cleveland, Ohio, USA faulxm@ccf.org.ORCID 0000-0002-6946-778X
Cleveland Clinic · USCleveland Clinic Lerner College of Medicine · USTokushima University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the use of echocardiography in patients hospitalised with suspected coronavirus infection and to assess its impact on clinical management.

methodsWe studied 79 adults from a prospective registry of inpatients with suspected coronavirus infection at a single academic centre. Echocardiographic indications included abnormal biomarkers, shock, cardiac symptoms, arrhythmia, worsening hypoxaemia or clinical deterioration. Study type (limited or complete) was assessed for each patient. The primary outcome measure was echocardiography-related change in clinical management, defined as intensive care transfer, medication changes, altered ventilation parameters or subsequent cardiac procedures within 24 hours of echocardiography. Coronavirus-positive versus coronavirus-negative patient groups were compared. The relationship between echocardiographic findings and coronavirus mortality was assessed.

results56 patients were coronavirus-positive and 23 patients were coronavirus-negative with symptoms attributed to other diagnoses. Coronavirus-positive patients more often received limited echocardiograms (70% vs 26%, p=0.001). The echocardiographic indication for coronavirus-infected patients was frequently worsening hypoxaemia (43% vs 4%) versus chest pain, syncope or clinical heart failure (23% vs 44%). Echocardiography changed management less frequently in coronavirus-positive patients (18% vs 48%, p=0.01). Among coronavirus-positive patients, 14 of 56 (25.0%) died during hospitalisation. Those who died more often had echocardiography to evaluate clinical deterioration (71% vs 24%) and had elevated right ventricular systolic pressures (37 mm Hg vs 25 mm Hg), but other parameters were similar to survivors.

conclusionsEchocardiograms performed on hospitalised patients with coronavirus infection were often technically limited, and their findings altered patient management in a minority of patients.

Indexed as

Echocardiography, DopplerAgedAged, 80 and overClinical Decision-MakingCOVID-19FemaleHeartHeart DiseasesHospitalizationHumansMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesbiomarkersCOVID-19echocardiographyquality of healthcare

Identifiers

PMID34376573
PMCPMC8359860
OpenAlexW3191631369

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.