ArticleInternational journal of spine surgery2021
Synthetic Bone Graft Materials in Spine Fusion: Current Evidence and Future Trends.
Article in International journal of spine surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Ceramic bone graft substitute vs autograft in XLIF: a prospective randomized single-center evaluation of radiographic and clinical outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Trial
- Comparative analysis of autograftJournal of spine surgery (Hong Kong) · 2026Article
- Practical Strategies for Bone Graft Selection in Spinal Fusion: A Narrative Review with Regional Perspectives.Spine surgery and related research · 2026Review
- A Pre-Set Calcium Sulfate/Hydroxyapatite Biomaterial as an Antibiotic-Eluting Bone Extender and a Carrier for BMP-2: A Pilot Study in a Rabbit Posterolateral Spinal Fusion Model.Journal of functional biomaterials · 2026Article
- A Review of Synthetic Bone Grafts in Lumbar Interbody Fusion.Bioengineering (Basel, Switzerland) · 2026Review
- What Graft Should Be Used in Pediatric Posterior Spinal Fusion? Current Trends and Perspective Among Experts.Journal of the Pediatric Orthopaedic Society of North America · 2026Article
- A pre-market, open-label, single-arm study to evaluate b.Bone for posterolateral fusion treatment of degenerative thoracolumbar, lumbar or lumbosacral spinal disease (b.Spine clinical trial).Frontiers in bioengineering and biotechnology · 2026Article
- Comparative Performance of Calcium Phosphate Grafts and Iliac Crest Autograft in Posterolateral Spinal Fusion in Rabbits.JOR spine · 2025Article
- Article
- In Vivo Performance of a Novel Hyper-Crosslinked Carbohydrate Polymer Bone Graft Substitute for Spinal Fusion.Bioengineering (Basel, Switzerland) · 2025Article
- A safe, novel and ingenious method for autogenous bone graft storage in spine surgery with constrained resources - operative site as the bone bank.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Use of ceramic synthetic allografts in spine surgery: a narrative review with early basic science and clinic data of novel nanosynthetic bone graft.Journal of spine surgery (Hong Kong) · 2024Review
- How to improve the mechanical safety of a novel spinal implant while saving costs and time.JOR spine · 2024Review
- Injectable bioactive poly(propylene fumarate) and polycaprolactone based click chemistry bone cement for spinal fusion in rabbits.Journal of biomedical materials research. Part A · 2024Article
- Drug eluting bioactive glass ceramics for fusion in spondylodiscitis: a pilot study.Neurosurgical review · 2024Observational
- Spinal fusion of biodegradable poly(propylene fumarate) and poly(propylene fumarate-co-caprolactone) copolymers in rabbits.Journal of orthopaedics · 2024Article
- Advances in Synthetic Grafts in Spinal Fusion Surgery.International journal of spine surgery · 2023Article
- Article
- Chitosan 3D scaffolds with resolvin D1 for vertebral arthrodesis: a pilot study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Use of biphasic calcium phosphate versus demineralized bone matrix: retrospective clinical and CT analysis of posterolateral fusion results.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Historically, iliac crest bone autograft has been considered the gold standard bone graft substitute for spinal fusion. However, the significant morbidity associated with harvesting procedures has influenced decision-making and practice patterns. To minimize these side effects, many clinicians have pursued the use of bone graft extenders to minimize the amount of autograft required for fusion in certain applications. Synthetic materials, including a variety of ceramic compounds, are a class that has been studied extensively as bone graft extenders. These have been used in combination with a wide array of other biomaterials and investigated in a variety of different spine fusion procedures. This review will summarize the current evidence of different synthetic materials in various spinal fusion procedures and discuss the future of novel synthetics.
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Registered trials
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