Evidence map›Paper›PMID 34376307›Full record

ArticleVaccine2021

Influenza vaccine acceptance and hesitancy among adults hospitalized with severe acute respiratory illnesses, United States 2019-2020.

Kelsey L Lytle, Sean P Collins, Leora R Feldstein, Adrienne H Baughman, Samuel M Brown, Jonathan D Casey, Heidi L Erickson, Matthew C Exline, D Clark Files, Kevin W Gibbs and 16 more

Open access · greenAbstract read
In one paragraph

Article in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Vaccine hesitancy in an allergy and immunology clinic in an underserved community.The journal of allergy and clinical immunology. Global · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 11 institutions in 1 country.

Kelsey L LytleVanderbilt University Medical Center, Nashville, TN, USA.
Sean P CollinsVanderbilt University Medical Center, Nashville, TN, USA.
Leora R FeldsteinCenters for Disease Control and Prevention, Atlanta, GA, USA.
Adrienne H BaughmanVanderbilt University Medical Center, Nashville, TN, USA.
Samuel M BrownIntermountain Medical Center and University of Utah, Salt Lake City, UT, USA.
Jonathan D CaseyVanderbilt University Medical Center, Nashville, TN, USA.
Heidi L EricksonHennepin County Medical Center and the University of Minnesota Medical School, Minneapolis, MN, USA.
Matthew C ExlineThe Ohio State University, Columbus, OH, USA.
D Clark FilesWake Forest School of Medicine, Winston Salem North Carolina, USA.
Kevin W GibbsWake Forest School of Medicine, Winston Salem North Carolina, USA.
Adit A GindeUniversity of Colorado School of Medicine, Aurora, CO, USA.
Michelle N GongMontefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Carlos G GrijalvaVanderbilt University Medical Center, Nashville, TN, USA.
Akram KhanOregon Health & Sciences University, Portland, OR, USA.
Christopher J LindsellVanderbilt University Medical Center, Nashville, TN, USA.
Ithan D PeltanIntermountain Medical Center and University of Utah, Salt Lake City, UT, USA.
Matthew E PrekkerHennepin County Medical Center and the University of Minnesota Medical School, Minneapolis, MN, USA.
Todd W RiceVanderbilt University Medical Center, Nashville, TN, USA.
Nathan I ShapiroBeth Israel Deaconess Medical Center, Boston, MA, USA.
Jay S SteingrubBaystate Medical Center, Springfield, MA, USA.
William B StubblefieldVanderbilt University Medical Center, Nashville, TN, USA.
Mark W TenfordeCenters for Disease Control and Prevention, Atlanta, GA, USA.
Kelsey N WomackVanderbilt University Medical Center, Nashville, TN, USA.
Manish M PatelCenters for Disease Control and Prevention, Atlanta, GA, USA.
Wesley H SelfVanderbilt University Medical Center, Nashville, TN, USA. Electronic address: wesley.self@vumc.org.
Influenza and Other Viruses in the Acutely Ill (IVY) Network
Vanderbilt University Medical Center · USCenters for Disease Control and Prevention · USUniversity of Minnesota · USUniversity of Utah · USWake Forest University · USAlbert Einstein College of Medicine · USBaystate Medical Center · USBeth Israel Deaconess Medical Center · USOregon Health & Science University · USThe Ohio State University · USUniversity of Colorado Denver · US

Funding

Clinical and Translational Training Program in Pulmonary MedicineT32HL087738 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lorraine B Ware · 2007 to 2026
$7.0M
Mentoring in transmission of influenza and strategies for preventionK24AI148459 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GRIJALVA, CARLOS G · 2020 to 2024
$893k
Prehospital Activation of ED Teams to Improve Sepsis CareK23GM129661 · NIGMS · IHC HEALTH SERVICES, INC. · PI PELTAN, ITHAN DANIEL · 2019 to 2023
$786k
NHLBI NIH HHS T32 HL087738NIAID NIH HHS K24 AI148459NIGMS NIH HHS K23 GM129661
6 · The paper itself

Abstract

introductionUnderstanding patient factors associated with not being vaccinated is essential for successful implementation of influenza vaccination programs.

methodsWe enrolled adults hospitalized with severe acute respiratory illness at 10 United States (US) hospitals during the 2019-2020 influenza season. We interviewed patients to collect data about influenza vaccination, sociodemographic characteristics, and vaccine perceptions.

resultsAmong 679 participants, 264 (38.9%) reported not receiving influenza vaccination. Among those not vaccinated, 135 (51.1%) reported choosing not to receive a vaccine because of perceived ineffectiveness (36.7%) or risk (14.4%) of influenza vaccination. Sociodemographic factors associated with not being vaccinated included no medical insurance (aOR = 6.42; 95% CI: 2.52-16.38) and being non-White or Hispanic (aOR = 1.54, 95% CI: 1.02-2.32).

conclusionsOptimizing uptake of influenza vaccination in the US may be improved by educational programs regarding vaccine safety and effectiveness and enhancing vaccine access, particularly among non-White and Hispanic Americans and those without medical insurance.

Indexed as

Influenza, HumanInfluenza VaccinesAdultHumansUnited StatesVaccinationInfluenza VaccinesInfluenzaMedical insuranceVaccinationVaccine acceptanceVaccine hesitancy

Identifiers

PMID34376307
PMCPMC8588478
OpenAlexW3187272397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.