ArticleJournal of the International Neuropsychological Society : JINS2022
Midlife Vascular Factors and Prevalence of Mild Cognitive Impairment in Late-Life in Mexico.
Article in Journal of the International Neuropsychological Society : JINS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Magnitude and predictors of mild cognitive impairment among older populations in Africa: a systematic review and meta-analysis.Translational psychiatry · 2025Pooled it
- The complex burden of determining prevalence rates of mild cognitive impairment: A systematic review.Frontiers in psychiatry · 2022Pooled it
- Sensory impairment and cognitive impairment among older adults in rural China: personal responsibility for health as a possible moderator?BMC geriatrics · 2026Article
- Differential Improvement in Memory and Executive Functions: Personalized Exercise versus Acupuncture for Mild Cognitive Impairment in Stroke-prone Individuals.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Article
- Prevalence of dementia and mild cognitive impairment in the Mexican population: evidence from Mex-Cog, a harmonized cognitive assessment protocol study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Drought and cognitive function in older adults: results from the Mexican health and aging study.Environment international · 2026Article
- Harmonized Cognitive Assessment Protocol: What makes an HCAP an HCAP? An adaptive architecture for measuring cognitive aging around the world.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Dose-response and cumulative effects of educational attainment and occupational complexity on mid to late life cognitive performance in Brazil and Mexico.Alzheimer's & dementia. Behavior & socioeconomics of aging · 2025Article
- Role of Micronutrient Supplementation in Promoting Cognitive Healthy Aging in Latin America: Evidence-Based Consensus Statement.Nutrients · 2025Review
- Development and validation of a predictive model for frailty risk in older adults with cardiovascular-metabolic comorbidities.Frontiers in public health · 2025Article
- Association between hypertension and dementia risk in low- and middle-income countries: A systematic review.JAR life · 2025Review
- Care Need, Caregiver Availability, and Care Receipt: Variations Across Countries and Over Time in Three Middle-Income Countries.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- [Cognitive function groups in older people and risk factors].Revista medica del Instituto Mexicano del Seguro Social · 2024Article
- Prevalence of DSM-5 mild and major neurocognitive disorder in India: Results from the LASI-DAD.PloS one · 2024Article
- Vascular cognitive impairment and dementia: a narrative review.Dementia & neuropsychologia · 2024Review
- Brain health index as a predictor of possible vascular dementia in the Mexican health and aging study 2012-2015.PloS one · 2024Article
- Risk factors for cognitive dysfunction amongst patients with cardiovascular diseases.Frontiers in public health · 2024Article
- Harmonisation of later-life cognitive function across national contexts: results from the Harmonized Cognitive Assessment Protocols.The lancet. Healthy longevity · 2023Article
- The Mex-Cog cognitive assessment battery: discriminant analysis of the cognitive performance profile in older adults.Salud publica de Mexico · 2023Article
- Measurement differences in the assessment of functional limitations for cognitive impairment classification across geographic locations.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
objectiveTo estimate the prevalence of mild cognitive impairment (MCI) and its subtypes and investigate the impact of midlife cardiovascular risk factors on late-life MCI among the aging Mexican population.
methodAnalyses included a sample of non-demented adults over the age of 55 living in both urban and rural areas of Mexico (N = 1807). MCI diagnosis was assigned based on a comprehensive cognitive assessment assessing the domains of memory, executive functioning, language, and visuospatial ability. The normative sample was selected by means of the robust norms approach. Cognitive impairment was defined by a 1.5-SD cut-off per cognitive domain using normative corrections for age, years of education, and sex. Risk factors included age, education, sex, rurality, depression, insurance status, workforce status, hypertension, diabetes, stroke, and heart disease.
resultsThe prevalence of amnestic MCI was 5.9%. Other MCI subtypes ranged from 4.2% to 7.7%. MCI with and without memory impairment was associated with older age (OR = 1.01 [1.01, 1.05]; OR = 1.03 [1.01, 1.04], respectively) and residing in rural areas (OR = 1.49 [1.08, 2.06]; OR = 1.35 [1.03, 1.77], respectively). Depression (OR = 1.07 [1.02, 1.12]), diabetes (OR = 1.37 [1.03, 1.82]), and years of education (OR = 0.94 [0.91, 0.97]) were associated with MCI without memory impairment. Midlife CVD increased the odds of MCI in late-life (OR = 1.76 [1.19, 2.59], which was driven by both midlife hypertension and diabetes (OR = 1.70 [1.18, 2.44]; OR = 1.88 [1.19, 2.97], respectively).
conclusionsOlder age, depression, low education, rurality, and midlife hypertension and diabetes were associated with higher risk of late-life MCI among older adults in Mexico. Our findings suggest that the causes of cognitive impairment are multifactorial and vary by MCI subtype.
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