Evidence map›Paper›PMID 34376065›Full record

ReviewAdvances in wound care2022

Debridement of Diabetic Foot Ulcers.

David Dayya, Owen J O'Neill, Tania B Huedo-Medina, Nusrat Habib, Joanna Moore, Kartik Iyer

Registry-linked trialAbstract readReview
In one paragraph

Review in Advances in wound care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06886633 (The Effect of Breathing Exercise and Pressurized Cold Application on Pain and Anxiety During Sharp Debridement in Diabetic Foot Ulcers), which is not on this map. Cited by 70 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06886633 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

The Effect of Breathing Exercise and Pressurized Cold Application on Pain and Anxiety During Sharp Debridement in Diabetic Foot Ulcers

TypeinterventionalSponsorHarran UniversityRan2025 to 2025Enrolled78ConditionsDiabetic Foot UlcerArmsBreathing exercise, Experimental: Pressurized Cold Application Group
3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Skin Organoids in Diabetic Chronic Wounds: Current Status and Future Perspectives.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026
    Review
  13. Review
  14. Article
  15. Article
  16. Infection and drug resistance · 2026
    Article
  17. Article
  18. Review
  19. Observational
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David DayyaDivision of Undersea and Hyperbaric Medicine, Department of Surgery, Phelps Hospital Northwell Health, Sleepy Hollow, New York, USA.ORCID 0000-0002-4779-5133
Owen J O'NeillDivision of Undersea and Hyperbaric Medicine, Department of Surgery, Phelps Hospital Northwell Health, Sleepy Hollow, New York, USA.
Tania B Huedo-MedinaDepartment of Allied Health Sciences, University of Connecticut, Storrs, Connecticut, USA.
Nusrat HabibDepartment of Allied Health Sciences, University of Connecticut, Storrs, Connecticut, USA.
Joanna MooreDepartment of Medicine, Norwalk Hospital, Norwalk, Connecticut, USA.
Kartik IyerDepartment of Medicine, Norwalk Hospital, Norwalk, Connecticut, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic foot ulcerations have devastating complications, including amputations, poor quality of life, and life-threatening infections. Diabetic wounds can be protracted, take significant time to heal, and can recur after healing. They are costly consuming health care resources. These consequences have serious public health and clinical implications. Debridement is often used as a standard of care. Debridement consists of both nonmechanical (autolytic, enzymatic) and mechanical methods (sharp/surgical, wet to dry debridement, aqueous high-pressure lavage, ultrasound, and biosurgery/maggot debridement therapy). It is used to remove nonviable tissue, to facilitate wound healing, and help prevent these serious outcomes. What are the various forms and rationale behind debridement? This article comprehensively reviews cutting-edge methods and the science behind debridement and diabetic foot ulcers.

Indexed as

Diabetes MellitusDiabetic FootFoot UlcerDebridementHumansQuality of LifeWound Healingdebridementdiabetesdressingsfoot ulcerspublic health

Identifiers

PMID34376065
PMCPMC9527061

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.