ArticleAnnals of coloproctology2021
Has the COVID-19 Pandemic Caused Upshifting in Colorectal Cancer Stage?
Article in Annals of coloproctology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of the Sars-Cov-2 outbreak on the initial clinical presentation of new solid cancer diagnoses: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- Inadvertent laparoscopic lavage of perforated colon cancer: a systematic review.Langenbeck's archives of surgery · 2024Pooled it
- The impact of extended invitation intervals on stage distribution of screen-detected and interval cancer within the Dutch colorectal cancer screening program.International journal of cancer · 2025Article
- The COVID-19 pandemic and clinical characteristics of colorectal cancer: a multicenter retrospective study.Scientific reports · 2025Article
- Measuring the impact of COVID-19 on cancer survival using an interrupted time series analysis.JNCI cancer spectrum · 2024Article
- Decreased Positive Fecal Occult Blood Tests and Delayed Medical Presentation for Colorectal Cancer during the Initial COVID-19 Pandemic Period: A Single-center Experience.Journal of the anus, rectum and colon · 2024Article
- Impact of COVID-19 Pandemic on the Clinical and Pathologic Characteristics of Colorectal Cancer: A Retrospective Multicenter Study in South Korea.Cancer management and research · 2024Article
- Influence of the COVID-19 Pandemic on the Treatment Patterns and Outcomes of Colorectal Cancer.Ewha medical journal · 2023Review
- Clinical presentation, management, screening and surveillance for colorectal cancer during the COVID-19 pandemic.World journal of clinical cases · 2022Review
- The effect of the COVID-19 pandemic on the outcomes of surgically treated colorectal diseases: a retrospective cohort study.Annals of surgical treatment and research · 2022Article
- Surgical safety in the COVID-19 era: present and future considerations.Annals of surgical treatment and research · 2022Review
- Short-Term Impact of Temporary Shutdown of a University-Affiliated Hospital on Patients With Colorectal Cancer During the Coronavirus Disease 2019 Pandemic.Journal of Korean medical science · 2022Article
- Review
- Epidemiology, Risk Factors, and Prevention of Colorectal Cancer-An English Version.Journal of the anus, rectum and colon · 2022Review
- No evidence of delay in colorectal cancer diagnosis during the COVID-19 pandemic in Gwangju and Jeonnam, KoreaEpidemiology and health · 2022Article
- Impact of the COVID-19 pandemic on the diagnosis, tumor characteristics, and survival outcomes of colorectal cancer: a retrospective cohort study.Annals of Saudi medicineArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCoronavirus disease 2019 (COVID-19) has affected many parts of daily life and healthcare, including cancer screening and diagnosis. The purpose of this study was to determine whether there was an upshift in the colorectal cancer stage at diagnosis due to delays related to the COVID-19 outbreak.
methodsFrom January to June of each year from 2017 to 2020, a total of 3,229 patients who were first diagnosed with colorectal cancer were retrospectively reviewed. Those enrolled from 2017 to 2019 were classified as the 'pre-COVID' group, and those enrolled in 2020 were classified as the 'COVID' group. The primary outcome was the rate of stage IV disease at the time of diagnosis.
resultsThere was no statistically significant difference in the proportion of stage IV patients between the pre-COVID and COVID groups (P = 0.19). The median preoperative carcinoembryonic antigen level in the COVID group was higher than in the pre-COVID group in all stages (all P < 0.05). In stage I, II patients who underwent radical surgery, the lymphatic invasion was more presented in COVID patients (P = 0.009).
conclusionWe did not find significant stage upshifting in colorectal cancer during the COVID-19 outbreak. However, there were more initially unresectable stage IV colorectal cancer patients with a low conversion rate to resectable status, and more patients had factors related to poor prognosis. These results may become more apparent over time, so it is vital not to neglect cancer screening to not delay the diagnosis during the COVID-19 epidemic.
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