Evidence map›Paper›PMID 34375549›Full record

ArticleOpen biology2021

Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod.

Faredin Alejevski, Michelle Leemans, Anne-Laure Gaillard, David Leistenschneider, Céline de Flori, Marion Bougerol, Sébastien Le Mével, Anthony Herrel, Jean-Baptiste Fini, Guillaume Pézeron and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Zebrafish: an important model for understanding scoliosis.Cellular and molecular life sciences : CMLS · 2022
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Faredin AlejevskiPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Michelle LeemansPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Anne-Laure GaillardPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
David LeistenschneiderPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Céline de FloriPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Marion BougerolPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Sébastien Le MévelPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Anthony HerrelMécanismes adaptatifs et évolution UMR 7179 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Jean-Baptiste FiniPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Guillaume PézeronPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Hervé TostivintPhysiologie moléculaire et adaptation UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Paris, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urp1 and Urp2 are two neuropeptides of the urotensin II family identified in teleost fish and mainly expressed in cerebrospinal fluid (CSF)-contacting neurons. It has been recently proposed that Urp1 and Urp2 are required for correct axis formation and maintenance. Their action is thought to be mediated by the receptor Uts2r3, which is specifically expressed in dorsal somites. In support of this view, it has been demonstrated that the loss of

Indexed as

Biological EvolutionGene Expression Regulation, DevelopmentalPhylogenySomatotypesAmino Acid SequenceAnimalsBase SequenceGene Expression ProfilingReceptors, G-Protein-CoupledSequence HomologyUrotensinsXenopus laevisXenopus ProteinsReceptors, G-Protein-Coupledurotensin IIUrotensinsXenopus Proteinscerebrospinal fluid-contacting neuronsmusclesscoliosisspinal cordurotensin IIXenopus

Identifiers

PMID34375549
PMCPMC8354755
OpenAlexW3190502214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.