Evidence map›Paper›PMID 34375439›Full record

ArticleCancer2021

Blood and Marrow Transplant Clinical Trials Network Study 1102 heralds a new era in hematopoietic cell transplantation in high-risk myelodysplastic syndromes: Challenges and opportunities in implementation.

Erica D Warlick, Celalettin Ustun, Astrid Andreescu, Anthony F Bonagura, Andrew Brunner, Abhinav B Chandra, James M Foran, Mark B Juckett, Tamila L Kindwall-Keller, Virginia M Klimek and 6 more

Open access · greenAbstract read
In one paragraph

Article in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 15 institutions in 1 country.

Erica D WarlickDivision of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0003-3888-2021
Celalettin UstunRush University Medical Center, Chicago, Illinois.
Astrid AndreescuNorthern Light Eastern Maine Medical Center, Lafayette Family Cancer Institute, Bangor, Maine.
Anthony F BonaguraOptum, North Wales, Pennsylvania.
Andrew BrunnerMassachusetts General Hospital, Boston, Massachusetts.
Abhinav B ChandraYuma Regional Medical Center, Yuma, Arizona.
James M ForanMayo Clinic Cancer Center, Mayo Clinic, Jacksonville, Florida.ORCID 0000-0003-1673-1708
Mark B JuckettSchool of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin.
Tamila L Kindwall-KellerUniversity of Virginia, Charlottesville, Virginia.
Virginia M KlimekMemorial Sloan Kettering Cancer Center, New York, New York.
Daniel F PeaseHennepin Healthcare, Minneapolis, Minnesota.
David P SteensmaDana-Farber Cancer Institute, Boston, Massachusetts.
Bryce M WaldmanCenter for International Blood and Marrow Transplant, Milwaukee, Wisconsin.
Mary M HorowitzCenter for International Blood and Marrow Transplant, Milwaukee, Wisconsin.
Linda J BurnsCenter for International Blood and Marrow Transplant, Milwaukee, Wisconsin.
Nandita KheraCollege of Medicine, Mayo Clinic, Phoenix, Arizona.ORCID 0000-0002-0577-3155
Versiti Blood Center of Wisconsin · USArizona Western College · USDana-Farber Cancer Institute · USEastern Maine Medical Center · USHennepin Healthcare Research Institute · USJacksonville College · USMassachusetts General Hospital · USMayo Clinic in Arizona · USMedical College of Wisconsin · USMemorial Sloan Kettering Cancer Center · USPolisher Research Institute · USRush University Medical Center · USUniversity of Minnesota · USUniversity of Virginia · USUniversity of Wisconsin–Madison · US

Funding

Blood and Marrow Transplant Clinical Trials Network DCC- The Medical College of Wisconsin, Inc.U24HL138660 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Steven M. DeVine, Mehdi Hussain Hamadani · 2017 to 2026
$71.4M
Easy-to-read Informed Consent for HCT Clinical TrialsU10HL069294 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HOROWITZ, MARY MARESCA · 2011 to 2016
$43.8M
BMT CTN Core - University of MinnesotaUG1HL069290 · NHLBI · UNIVERSITY OF MINNESOTA · PI Mark Juckett, Margaret L MacMillan · 2017 to 2026
$1.9M
NHLBI NIH HHS U10 HL069294NHLBI NIH HHS U24 HL138660NHLBI NIH HHS UG1 HL069290
6 · The paper itself

Abstract

lay summaryPeople who have advanced myelodysplastic syndromes (MDS) may live longer if they get a bone marrow transplant (BMT) instead of other therapies. However, only 15% of people with MDS actually get BMT. Experts say community physicians and transplant physicians should team up with insurance companies and patient advocacy groups to 1) spread this news about lifesaving advances in BMT, 2) ensure that everyone can afford health care, 3) provide emotional support for patients and families, 4) help patients and families get transportation and housing if they need to travel for transplant, and 5) improve care for people of under-represented racial and ethnic backgrounds.

Indexed as

Hematopoietic Stem Cell TransplantationMyelodysplastic SyndromesBone MarrowHumansTransplantation ConditioningTransplantation, Homologousallogeneic hematopoietic cell transplantationexpanded accessMDSmyelodysplastic syndromesreduce intensity conditioning

Identifiers

PMID34375439
PMCPMC8578257
OpenAlexW3188074061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.