Evidence map›Paper›PMID 34375304›Full record

ArticleAging2021

Long non-coding RNA ABHD11-AS1 promotes colorectal cancer progression and invasion through targeting the integrin subunit alpha 5/focal adhesion kinase/phosphoinositide 3 kinase/Akt signaling pathway.

Jia Luo, Yigui Jiang, Lianhui Wu, Dexiang Zhuo, Shengjun Zhang, Xiang Jiang, Yingming Sun, Yue Huang

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. MedComm · 2025
    Article
  10. Article
  11. Review
  12. The essential roles of lncRNAs/PI3K/AKT axis in gastrointestinal tumors.Frontiers in cell and developmental biology · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jia LuoDepartment of Gastroenterology, Affiliated Sanming First Hospital of Fujian Medical University, Sanming 365000, Fujian, China.
Yigui JiangDepartment of Gastroenterology, Affiliated Sanming First Hospital of Fujian Medical University, Sanming 365000, Fujian, China.
Lianhui WuDepartment of Endoscope Room, Affiliated Sanming First Hospital of Fujian Medical University, Sanming 365000, Fujian, China.
Dexiang ZhuoDepartment of Clinical Laboratory, Affiliated Sanming First Hospital of Fujian Medical University, Sanming 365000, Fujian, China.
Shengjun ZhangDepartment of Gastroenterology, Affiliated Sanming First Hospital of Fujian Medical University, Sanming 365000, Fujian, China.
Xiang JiangDepartment of Gynecology, Affiliated Sanming First Hospital of Fujian Medical University, Sanming 365000, Fujian, China.
Yingming SunDepartment of Medical and Radiation Oncology, Affiliated Sanming First Hospital of Fujian Medical University, Sanming 365000, Fujian, China.
Yue HuangDepartment of Gastroenterology, Affiliated Sanming First Hospital of Fujian Medical University, Sanming 365000, Fujian, China.
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding (lnc)RNA ABHD11-AS1 participates in the development and progress of various cancers, but its role in colorectal cancer (CRC) remains poorly known. In the present study, public database analysis and quantitative reverse transcription PCR of CRC and normal tissues showed that ABHD11-AS1 was overexpressed in CRC and associated with poor prognosis in CRC patients. Both

Indexed as

AnimalsApoptosisCell Line, TumorColorectal NeoplasmsDisease ProgressionFocal Adhesion Protein-Tyrosine KinasesGene Expression Regulation, NeoplasticHumansIntegrinsMaleMiceMice, Inbred BALB CNeoplasm InvasivenessPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktRNA, AntisenseABHD11 protein, humanFocal Adhesion Protein-Tyrosine KinasesIntegrinsITGA5 protein, humanPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktRNA, AntisenseRNA, Long NoncodingSerine Proteasescolorectal cancerlncRNA-ABHD11-AS1oncogene profilePI3K/Akt pathway

Identifiers

PMID34375304
PMCPMC8436895
OpenAlexW3187324951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.