Evidence map›Paper›PMID 34375020›Full record

ArticleCancer cytopathology2022

Liquid biopsy for the diagnosis of HPV-associated head and neck cancer.

Daniel L Faden

Open access · bronzeAbstract read
In one paragraph

Article in Cancer cytopathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Explore the role of ctHPVDNA kinetics during diagnosis and follow-up of HPV OPSCC.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Cell-Free HPV DNA Provides an Accurate and Rapid Diagnosis of HPV-Associated Head and Neck Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Daniel L FadenDepartment of Otolaryngology-Head and Neck Surgery, Mass Eye and Ear, Boston, Massachusetts.
Harvard University · US

Funding

Circulating HPV DNA as a Prediagnostic Marker of Oropharyngeal CancerR21CA267152 · NCI · UNIVERSITY OF KENTUCKY · PI FADEN, DANIEL, KUHS, KRYSTLE A. · 2022 to 2023
$431k
Cell free HPV DNA detection in the diagnostic and surgical settingsR03DE030550 · NIDCR · MASSACHUSETTS EYE AND EAR INFIRMARY · PI FADEN, DANIEL · 2022 to 2023
$336k
NCI NIH HHS R21 CA267152NIDCR NIH HHS R03 DE030550
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Head and Neck NeoplasmsOropharyngeal NeoplasmsPapillomavirus InfectionsDNA, ViralHumansLiquid BiopsyPapillomaviridaeDNA, Viralcell free DNAcfHPVDNAcirculating tumor DNAhead and neck cancerHPVhuman papilloma virusliquid biopsyoropharyngeal canceroropharyngeal squamous cell carcinoma

Identifiers

PMID34375020
PMCPMC10091195
OpenAlexW3193235886

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.