Evidence map›Paper›PMID 34374966›Full record

SynthesisEating and weight disorders : EWD2022

Alliance matters: but how much? A systematic review on therapeutic alliance and outcome in patients with anorexia nervosa and bulimia nervosa.

Janina Werz, Ulrich Voderholzer, Brunna Tuschen-Caffier

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Eating and weight disorders : EWD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  9. The Maudsley model of anorexia nervosa treatment for adolescents and emerging adults: A multi-centre cohort study.European eating disorders review : the journal of the Eating Disorders Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Janina WerzDepartment of Clinical Psychology and Psychotherapy, Albert-Ludwigs-University, Freiburg, Germany. jwerz@schoen-klinik.de.ORCID http://orcid.org/0000-0003-4846-0391
Ulrich VoderholzerSchön Klinik Roseneck, Am Roseneck 6, 83209, Prien am Chiemsee, Germany.
Brunna Tuschen-CaffierDepartment of Clinical Psychology and Psychotherapy, Albert-Ludwigs-University, Freiburg, Germany.
University of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients with eating disorders (ED) pose a high-risk group regarding relapse. The understanding of factors contributing to a better outcome is much-needed. Therapeutic alliance (TA) is one important, pantheoretical variable in the treatment process, which has shown to be connected with outcome. This review looks into a possible predictive effect of TA on outcome as well as related variables.

methodsA systematic review with pre-determined inclusion criteria following the PRISMA guidelines was conducted for studies published since 2014. Three previous reviews including studies up until 2014 were analyzed for studies matching our inclusion criteria. A total of 26 studies were included.

resultsThe results were heterogeneous between different patient groups. Regarding the predictive effect of TA, in adolescent samples, the TA of either the patients or their parents seems to impact outcome as well as completion. For adults, results are mixed, with a tendency to a greater impact of TA for anorexia nervosa (AN) patients, while some samples of adult bulimia nervosa (BN) patients did not find any relation between TA and outcome.

conclusionThe effect of TA on clinical outcome depends on the patient group. TA has a greater impact on adolescents, irrespective of diagnosis, and on adults with AN. The examined studies have different limitations which include small sample sizes and questionable study design. The examination of motivation as a potential influencing factor is recommended. LEVEL OF EVIDENCE: Level I, systematic review.

Indexed as

Anorexia NervosaBulimia NervosaFeeding and Eating DisordersTherapeutic AllianceAdolescentAdultHumansMotivationAnorexia nervosaBulimia nervosaEating disordersOutcomeSystematic reviewTherapeutic allianceWorking alliance

Identifiers

PMID34374966
PMCPMC9079014
OpenAlexW3191995348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.