Evidence map›Paper›PMID 34374933›Full record

ReviewHuman cell2021

Upregulation of lncRNA NIFK-AS1 in hepatocellular carcinoma by m

Yi-Tian Chen, Dan Xiang, Xiao-Yue Zhao, Xiao-Yuan Chu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Human cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. World journal of gastroenterology · 2025
    Article
  10. N6-methyladenosine-modified long non-coding RNAWorld journal of gastroenterology · 2024
    Article
  11. Article
  12. Epitranscriptomic RNA mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Non-coding RNA-Mediated N6-Methyladenosine (mNon-coding RNA research · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yi-Tian Chen *Department of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Zhongshan East Road 305, Nanjing, 210002, Jiangsu, China.
Dan Xiang *Department of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Zhongshan East Road 305, Nanjing, 210002, Jiangsu, China.
Xiao-Yue Zhao *Department of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Zhongshan East Road 305, Nanjing, 210002, Jiangsu, China.
Xiao-Yuan ChuDepartment of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Zhongshan East Road 305, Nanjing, 210002, Jiangsu, China. fbgpos@163.com.
Nanjing General Hospital of Nanjing Military Command · CNNanjing University · CN

Funding

National Natural Science Foundation of China No. 81972332
6 · The paper itself

Abstract

Long non-coding RNAs (LncRNAs) have recently emerged as vital regulators in the development and progression of hepatocellular carcinoma (HCC), providing new opportunities as novel therapeutic targets. Here we identified the lncRNA NIFK-AS1 as being highly expressed in HCC tissues and cells and showed this up-regulation resulted from METTL3-dependent m

Indexed as

Antineoplastic AgentsCarcinoma, HepatocellularCell Line, TumorCell MovementCell ProliferationDisease ProgressionDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticHumansIntracellular Signaling Peptides and ProteinsLiver NeoplasmsMethylationMethyltransferasesMolecular Targeted TherapyNeoplasm InvasivenessNuclear ProteinsAntineoplastic AgentsIntracellular Signaling Peptides and ProteinsMethyltransferasesMETTL3 protein, humanNIFK protein, humanNuclear ProteinsRNA, Long NoncodingSorafenibceRNAHCCm6ANIFK-AS1Sorafenib

Identifiers

PMID34374933
OpenAlexW3188669153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.