Evidence map›Paper›PMID 34374905›Full record

ArticleMagma (New York, N.Y.)2022

Evaluation of peripheral nerve acute crush injury in rabbits: comparison among diffusion kurtosis imaging, diffusion tensor imaging and electromyography.

Qi Wan, Yudong Yu, Yingying Bao, Jianfeng Hu, Peng Wang, Yu Peng, Xiaoying Xia, Yuting Liao, Jieqiong Liu, Xiaobin Xie and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Musculoskeletal Ultrasound and MRI in the Evaluation of Chemotherapy-Induced Peripheral Neuropathy: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Qi Wan *Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China.ORCID https://orcid.org/0000-0003-4222-2894
Yudong Yu *Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China.
Yingying BaoDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China.
Jianfeng HuDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China.
Peng WangDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China.
Yu PengDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China.
Xiaoying XiaDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China.
Yuting LiaoGE Healthcare, Guangzhou, China.
Jieqiong LiuDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China.
Xiaobin XieDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China.
Xinchun LiDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No. 151, Guangzhou, 510120, China. xinchunli@163.com.
First Affiliated Hospital of Guangzhou Medical University · CN

Funding

National Natural Science Foundation of China 81171800Science and Technology Planning Project of Guangdong Province 2016A020215168
6 · The paper itself

Abstract

objectiveDiffusion kurtosis imaging (DKI) has been proven to provide additional value for assessing many central nervous system diseases compared with conventional diffusion tensor imaging (DTI); however, whether it has the same value in peripheral nerve injury is unclear. This study aimed to investigate the performance of DKI, DTI, and electromyography (EMG) in evaluating peripheral nerve crush injury (PNCI) in rabbits. MATERIALS AND

methodsA total of 27 New Zealand white rabbits were selected to establish a PNCI model. Longitudinal DTI, DKI, and EMG were evaluated before surgery and 1 day, 3 days, 1 week, 2 weeks, 4 weeks, 6 weeks, and 8 weeks after surgery. At each time point, two rabbits were randomly selected for pathological examination.

resultsThe results showed that fractional anisotropy (FA) derived from both DKI and DTI demonstrated a significant difference between injured and control nerves at all time points (all P < 0.005) mean kurtosis of the injured nerve was lower than that on the control side after 2-8 weeks (all P < 0.05). No statistically significant difference was found in radial kurtosis, axial kurtosis, and apparent diffusion coefficient at almost every time point. The difference in compound muscle action potential (CMAP) of the bilateral gastrocnemius at each time point was statistically significant (all P < 0.001).

conclusionsCMAP was a sensitive and reliable method to assess acute PNCI without being affected by perineural edema. DKI may not be superior to DTI in evaluating peripheral nerves, DTI with a shorter scanning time was preferred as an effective choice for evaluating acute peripheral nerve traumatic injury.

Indexed as

Crush InjuriesPeripheral Nerve InjuriesAnimalsDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingElectromyographyPeripheral NervesRabbitsDiffusion kurtosis imagingDiffusion tensor imagingElectromyographyMagnetic resonance imagingPeripheral nerve injury

Identifiers

PMID34374905
OpenAlexW3191664275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.