ArticleNeuroradiology2022
Altered thalamo-cortical functional connectivity in patients with vestibular migraine: a resting-state fMRI study.
Article in Neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Network localization of regional intrinsic neural activity alterations in migraine and their neurochemical correlates.Frontiers in neurology · 2026Pooled it
- The altered functional status in vestibular migraine: A meta-analysis.Brain and behavior · 2024Pooled it
- Exploring the complex relationship between vestibular symptoms and migraine: a resting‑state functional MRI study.Brain imaging and behavior · 2026Article
- Vestibular cortex-related effective connectivity signatures: characterization and differentiation of vestibular migraine patients via magnetic resonance imaging and machine learning.The journal of headache and pain · 2026Article
- Early life stress induces brain-wide electrical network predisposition to migraine.The journal of headache and pain · 2026Article
- Auditory pathways in migraine and vestibular migraine: New insights into sound sensitivity and spectral resolution dysfunction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Posterior insular cortex hyperactivation drives vestibular migraine and comorbid anxiety.The journal of headache and pain · 2026Article
- Altered functional connectivity density in the prefrontal-limbic-visual networks of vestibular migraine.Scientific reports · 2026Article
- Chronic dizziness: neuro-sensitization and psycho-sensitization.Frontiers in integrative neuroscience · 2026Review
- Persistent postural-perceptual dizziness versus vestibular migraine: A narrative review.Headache · 2026Review
- Cortical morphological alterations in vestibular migraine: insights from surface-based morphometry and machine learning.The journal of headache and pain · 2025Article
- Changes in the functional brain networks and graph theory analysis of patients with epilepsy and comorbid migraine without aura.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Functional and Structural Differences of Brain in Patients With Vestibular Migraine: A Resting-State Functional MRI and DTI Study.Brain and behavior · 2025Article
- Resting-state fMRI reveals brain functional alterations linked to balance disorders in vestibular migraine patients.Scientific reports · 2025Article
- Evaluating the Role of Coenzyme Q10 in Migraine Therapy-A Narrative Review.Antioxidants (Basel, Switzerland) · 2025Review
- Why is vestibular migraine associated with many comorbidities?Journal of neurology · 2024Review
- Disrupted gray matter connectome in vestibular migraine: a combined machine learning and individual-level morphological brain network analysis.The journal of headache and pain · 2024Article
- Brain Functional Alterations in Patients With Benign Paroxysmal Positional Vertigo Demonstrate the Visual-Vestibular Interaction and Integration.Brain and behavior · 2024Article
- Focused Update on Migraine and Vertigo Comorbidity.Current pain and headache reports · 2024Review
- Aberrant cerebral blood flow and functional connectivity in patients with vestibular migraine: a resting-state ASL and fMRI study.The journal of headache and pain · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
purposeTo explore the functional connectivity (FC) between the bilateral thalamus and the other brain regions in patients with vestibular migraine (VM).
methodsResting-state fMRI and 3D-T1 data were collected from 37 patients with VM during the interictal period and 44 age-, gender-, and years of education-matched healthy controls (HC). The FC of the bilateral thalamus was analyzed using a standard seed-based whole-brain correlation method. Furthermore, the correlations between thalamus FC and clinical characteristics of patients were investigated using Pearson's partial correlation.
resultsCompared with HC, VM patients showed decreased FC between the left thalamus and the left anterior cingulate cortex (ACC), bilateral insular and right supplementary motor cortex. We also observed decreased FC between the right thalamus and the left insular and ACC in VM patients. Furthermore, patients with VM also exhibited increased FC between the left thalamus and the right precuneus and middle frontal gyrus, between the right thalamus and superior parietal lobule. FC between the right thalamus and the left insular was negatively correlated with disease duration (p = 0.019, r = - 0.399), FC between the left thalamus and the left ACC was negatively correlated with HIT-6 score (p = 0.004, r = - 0.484).
conclusionVM patients showed altered FC between thalamus and brain regions involved in pain, vestibular and visual processing, which are associated with specific clinical features. Specifically, VM patients showed reduced thalamo-pain and thallamo-vestibular pathways, while exhibited enhanced thalamo-visual pathway, which provided first insight into the underlying functional brain connectivity in VM patients.
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