Evidence map›Paper›PMID 34374796›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

AI-enhanced simultaneous multiparametric

V Romeo, P Clauser, S Rasul, P Kapetas, P Gibbs, P A T Baltzer, M Hacker, R Woitek, T H Helbich, K Pinker

Registry-linked trialAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06370234 (The Prediction Model of Neoadjuvant Chemotherapy Response for Breast Cancer Based on The Parametric Dynamics Features of The Pretreatment and Early-Treatment MR-PET and QDS-IR Images.), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06370234 nacompletednot on this map

The Prediction Model of Neoadjuvant Chemotherapy Response for Breast Cancer Based on The Parametric Dynamics Features of The Pretreatment and Early-Treatment MR-PET and QDS-IR Images.

TypeinterventionalSponsorNational Taiwan University HospitalRan2015 to 2020Enrolled60ConditionsBreast Cancer, Chemotherapy Effect, Diffusion Weighted MRI, PET ImagingArmsWhole body 18F-FDG Positron Emission Tomography
3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Uptake Patterns of [Cancers · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Clinician-driven automated data preprocessing in nuclear medicine AI environments.European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Machine learning and new insights for breast cancer diagnosis.The Journal of international medical research · 2024
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Breast PET/MRI Hybrid Imaging and Targeted Tracers.Journal of magnetic resonance imaging : JMRI · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

V RomeoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Via S. Pansini 5, 80138, Naples, Italy.
P ClauserDepartment of Biomedical Imaging and Image-Guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Wien, Austria.
S RasulDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Wien, Austria.
P KapetasDepartment of Biomedical Imaging and Image-Guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Wien, Austria.
P GibbsDepartment of Radiology, Breast Imaging Service, Memorial Sloan Kettering Cancer Center, 300 E 66th Street, New York, NY, 10065, USA.
P A T BaltzerDepartment of Biomedical Imaging and Image-Guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Wien, Austria.
M HackerDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Wien, Austria.
R WoitekDepartment of Biomedical Imaging and Image-Guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Wien, Austria.
T H HelbichDepartment of Biomedical Imaging and Image-Guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Wien, Austria. thomas.helbich@meduniwien.ac.at.
K PinkerDepartment of Biomedical Imaging and Image-Guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Wien, Austria.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeTo assess whether a radiomics and machine learning (ML) model combining quantitative parameters and radiomics features extracted from simultaneous multiparametric

methodsA population of 102 patients with 120 breast lesions (101 malignant and 19 benign) detected on ultrasound and/or mammography was prospectively enrolled. All patients underwent hybrid

resultsEight radiomics models were developed. The integrated model combining MTT and ADC with radiomics features extracted from PET and ADC images obtained the highest accuracy for breast cancer diagnosis (AUC 0.983), although its accuracy was not significantly higher than that of expert reader review (AUC 0.868) (p = 0.508).

conclusionA radiomics and ML model combining quantitative parameters and radiomics features extracted from simultaneous multiparametric

Indexed as

Breast NeoplasmsFluorodeoxyglucose F18FemaleHumansMagnetic Resonance ImagingRetrospective StudiesSupport Vector MachineFluorodeoxyglucose F1818F-FDG PET/MRIArtificial intelligenceBreast cancerRadiomics

Identifiers

PMID34374796
PMCPMC8803815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.