Evidence map›Paper›PMID 34374780›Full record

ArticleIntegrative and comparative biology2022

Reintegrating Biology Through the Nexus of Energy, Information, and Matter.

Kim L Hoke, Sara L Zimmer, Adam B Roddy, Mary Jo Ondrechen, Craig E Williamson, Nicole R Buan

Abstract read
In one paragraph

Article in Integrative and comparative biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kim L HokeDepartment of Biology, Colorado State University, Fort Collins, CO 80523-1878, USA.
Sara L ZimmerDepartment of Biomedical Sciences, University of Minnesota Medical School, Duluth campus, Duluth, MN 55812, USA.
Adam B RoddyDepartment of Biological Sciences, Institute of Environment, Florida International University, Miami, FL 33199, USA.
Mary Jo OndrechenDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
Craig E WilliamsonDepartment of Biology, Miami University, Oxford, OH 45056, USA.
Nicole R BuanDepartment of Biochemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0662, USA.

Funding

Control of polyadenylation in the parasite mitochondrionR15AI135885 · NIAID · UNIVERSITY OF MINNESOTA DULUTH · PI ZIMMER, SARA LANA · 2018 to 2018
$441k
NIAID NIH HHS R15 AI135885
6 · The paper itself

Abstract

Information, energy, and matter are fundamental properties of all levels of biological organization, and life emerges from the continuous flux of matter, energy, and information. This perspective piece defines and explains each of the three pillars of this nexus. We propose that a quantitative characterization of the complex interconversions between matter, energy, and information that comprise this nexus will help us derive biological insights that connect phenomena across different levels of biological organization. We articulate examples from multiple biological scales that highlight how this nexus approach leads to a more complete understanding of the biological system. Metrics of energy, information, and matter can provide a common currency that helps link phenomena across levels of biological organization. The propagation of energy and information through levels of biological organization can result in emergent properties and system-wide changes that impact other hierarchical levels. Deeper consideration of measured imbalances in energy, information, and matter can help researchers identify key factors that influence system function at one scale, highlighting avenues to link phenomena across levels of biological organization and develop predictive models of biological systems.

Indexed as

BiologyAnimals

Identifiers

PMID34374780
PMCPMC8826246

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.