Evidence map›Paper›PMID 34374748›Full record

ArticleBlood advances2021

ASH, ABHH, ACHO, Grupo CAHT, Grupo  CLAHT, SAH, SBHH, SHU, SOCHIHEM, SOMETH, Sociedad Panameña de Hematología, SPH, and SVH 2021 guidelines for management of venous thromboembolism in Latin America.

Ignacio Neumann, Ariel Izcovich, Ricardo Aguilar, Guillermo León Basantes, Patricia Casais, Cecilia C Colorio, María Cecilia Guillermo Esposito, Pedro P García Lázaro, Luis A Meillon-García, Jaime Pereira and 7 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 10 countries.

Ignacio NeumannDepartment of Internal Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Ariel IzcovichHospital Alemán, Buenos Aires, Argentina.ORCID 0000-0001-9053-4396
Ricardo AguilarServicio de Hematología, Complejo Hospitalario Dr. Arnulfo Arias Madrid, Panama City, Panama.
Guillermo León BasantesClínica Universitaria Colombia, Bogotá, Colombia.
Patricia CasaisEpidemiología Clínica y Evidencia, Instituto de Investigaciones en Salud Pública, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0002-0121-150X
Cecilia C ColorioFundación Favaloro, Buenos Aires, Argentina.
María Cecilia Guillermo EspositoHospital de Clínicas Dr. Manuel Quintela, Montevideo, Uruguay.ORCID 0000-0003-2748-8889
Pedro P García LázaroFaculty of Medicine, Universidad Privada Antenor Orrego, Trujillo, Peru.ORCID 0000-0003-4521-4048
Luis A Meillon-GarcíaThe ABC Medical Center, Mexico City, Mexico.
Jaime PereiraDepartment of Hematology and Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID 0000-0003-0481-328X
Suely Meireles RezendeDepartment of Internal Medicine, Faculty of Medicine Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Juan Carlos SerranoUnidad Hematológica Especializada IPS, Cucuta, Colombia.
Mario L Tejerina ValleCaja Petrolera de Salud, La Paz, Bolivia.
Felipe VeraSchool of Health and Related Research, University of Sheffield, Sheffield, United Kingdom.ORCID 0000-0001-9460-4101
Lorena KarzulovicDepartment of Pediatrics, Pontificia Universidad Católica de Chile, Santiago, Chile; and.
Gabriel RadaDepartment of Internal Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Holger SchünemannDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.ORCID 0000-0003-3211-8479
Pontificia Universidad Católica de Chile · CLAntenor Orrego Private University · PECentro Médico ABC · MXComplejo Hospitalario Dr. Arnulfo Arias Madrid · PAFundación Universitaria Sanitas · COHospital Alemán · ARHospital de Clínicas · UYImpact · CAUniversidad de Buenos Aires · ARUniversidade Federal de Minas Gerais · BRUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVenous thromboembolism (VTE) is a common disease in Latin American settings. Implementing international guidelinn Aes in Latimerican settings requires additional considerations.

objectiveThe purpose of our study was to provide evidence-based guidelines about managing VTE for Latin American patients, clinicians, and decision makers.

methodsWe used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE)-ADOLOPMENT method to adapt recommendations from 2 American Society of Hematology (ASH) VTE guidelines (Treatment of VTE and Anticoagulation Therapy). ASH and local hematology societies formed a guideline panel comprised of medical professionals from 10 countries in Latin America. Panelists prioritized 18 questions relevant for the Latin American context. A knowledge synthesis team updated evidence reviews of health effects conducted for the original ASH guidelines and summarized information about factors specific to the Latin American context (ie, values and preferences, resources, accessibility, feasibility, and impact on health equity).

resultsThe panel agreed on 17 recommendations. Compared with the original guideline, 4 recommendations changed direction and 1 changed strength.

conclusionsThis guideline adolopment project highlighted the importance of contextualization of recommendations suggested by the changes to the original recommendations. The panel also identified 2 implementation priorities for the region: expanding the availability of home treatment and increasing the availability of direct oral anticoagulants (DOACs). The guideline panel made a conditional recommendation in favor of home treatment for individuals with deep venous thrombosis and a conditional recommendation for either home or hospital treatment for individuals with pulmonary embolism. In addition, a conditional recommendation was made in favor of DOACs over vitamin K antagonists for several populations.

Indexed as

Pulmonary EmbolismVenous ThromboembolismAnticoagulantsEvidence-Based MedicineHumansLatin AmericaAnticoagulants

Identifiers

PMID34374748
PMCPMC8361455
OpenAlexW3191156599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.