Evidence map›Paper›PMID 34374496›Full record

ReviewAlzheimer's & dementia : the journal of the Alzheimer's Association2022

National Institute on Aging seed funding enables Alzheimer's disease startups to reach key value inflection points.

Armineh L Ghazarian, Todd Haim, Samir Sauma, Pragati Katiyar

Open access · hybridAbstract readReview
In one paragraph

Review in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Armineh L GhazarianOffice of Small Business Research, National Institute on Aging, Bethesda, Maryland, USA.
Todd HaimOffice of Small Business Research, National Institute on Aging, Bethesda, Maryland, USA.ORCID 0000-0002-6408-2266
Samir SaumaOffice of Planning, Analysis, and Evaluation, National Institute on Aging, Bethesda, Maryland, USA.
Pragati KatiyarOffice of Planning, Analysis, and Evaluation, National Institute on Aging, Bethesda, Maryland, USA.
National Institute on Aging · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe National Institute on Aging (NIA) provides funding to academic researchers and small businesses working in the Alzheimer's Disease (AD) and AD-related dementia (ADRD) fields to help commercialize their products. The NIA uses Small Business Innovation Research (SBIR) awards to bridge the funding gap in the diagnostic, therapeutic, and care interventions areas, enabling startups to reach key value inflection points to achieve scientific milestones.

methodsOnly publicly available information is reported. The National Institutes of Health Report Portfolio Online Reporting Tool database and the commercial database Global Data, were used to track the progress of companies that received SBIR or Small Business Technology Transfer (STTR) funding from the NIA.

resultsSince 2008, the NIA has awarded $280 million-including $207 million from fiscal year (FY) 2015 to FY 2019-in new small business program awards for AD/ADRD research. DISCUSSION: NIA seed capital and mentoring programs are critical resources to help small businesses reach key value inflection points and advance their research from concept to commercialization.

Indexed as

Alzheimer DiseaseNational Institute on Aging (U.S.)HumansNational Institutes of Health (U.S.)Research PersonnelSmall BusinessUnited StatesNational Institute on Aging (NIA)National Institutes of Health (NIH)NIH Report Portfolio Online Reporting Tool (NIH RePORT)Small Business Education and Entrepreneurial Development (SEED)Small Business Innovation Research (SBIR)Small Business Technology Transfer (STTR)

Identifiers

PMID34374496
PMCPMC9291195
OpenAlexW3188890426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.