Evidence map›Paper›PMID 34374461›Full record

ArticleMedical physics2021

Single-pass metal artifact reduction using a dual-layer flat panel detector.

Linxi Shi, N Robert Bennett, Amy Shiroma, Mingshan Sun, Jin Zhang, Richard Colbeth, Josh Star-Lack, Minghui Lu, Adam S Wang

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In one paragraph

Article in Medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Linxi ShiDepartment of Radiology, Stanford University, Stanford, CA, USA.
N Robert BennettDepartment of Radiology, Stanford University, Stanford, CA, USA.
Amy ShiromaVarex Imaging Corporation, San Jose, CA, USA.
Mingshan SunVarex Imaging Corporation, San Jose, CA, USA.
Jin ZhangVarex Imaging Corporation, San Jose, CA, USA.
Richard ColbethVarex Imaging Corporation, San Jose, CA, USA.
Josh Star-LackVarex Imaging Corporation, San Jose, CA, USA.
Minghui LuVarex Imaging Corporation, San Jose, CA, USA.
Adam S WangDepartment of Radiology, Stanford University, Stanford, CA, USA.

Funding

STANFORD CANCER IMAGING TRAINING (SCIT) PROGRAMT32CA009695 · NCI · STANFORD UNIVERSITY · PI BRUCE L DANIEL, Jeremy Dahl · 1993 to 2026
$7.7M
Single-Shot Quantitative X-ray Imaging for Interventional ProceduresR21EB030080 · NIBIB · STANFORD UNIVERSITY · PI WANG, ADAM S · 2020 to 2022
$603k
NCI NIH HHS T32 CA009695NIBIB NIH HHS R21 EB030080NIH HHS R21EB030080NIH HHS T32CA009695
6 · The paper itself

Abstract

purposeMetal artifact remains a challenge in cone-beam CT images. Many image domain-based segmentation methods have been proposed for metal artifact reduction (MAR), which require two-pass reconstruction. Such methods first segment metal from a first-pass reconstruction and then forward-project the metal mask to identify them in projections. These methods work well in general but are limited when the metal is outside the scan field-of-view (FOV) or when the metal is moving during the scan. In the former, even reconstructing with a larger FOV does not guarantee a good estimate of metal location in the projections; and in the latter, the metal location in each projection is difficult to identify due to motion. Single-pass methods that detect metal in single-energy projections have also been developed, but often have imperfect metal detection that leads to residual artifacts. In this work, we develop a MAR method using a dual-layer (DL) flat panel detector, which improves performance for single-pass reconstruction.

methodsIn this work, we directly detect metal objects in projections using dual-energy (DE) imaging that generates material-specific images (e.g., soft tissue and bone), where the metal stands out in bone images when nonuniform soft tissue background is removed. Metal is detected via simple thresholding, and entropy filtration is further applied to remove false-positive detections. A DL detector provides DE images with superior temporal and spatial registration and was used to perform the task. Scatter correction was first performed on DE raw projections to improve the accuracy of material decomposition. One phantom mimicking a liver biopsy setup and a cadaver head were used to evaluate the metal reduction performance of the proposed method and compared with that of a standard two-pass reconstruction, a previously published sinogram-based method using a Markov random field (MRF) model, and a single-pass projection-domain method using single-energy imaging. The phantom has a liver steering setup placed in a hollow chest phantom, with embedded metal and a biopsy needle crossing the phantom boundary. The cadaver head has dental fillings and a metal tag attached to its surface. The identified metal regions in each projection were corrected by interpolation using surrounding pixels, and the images were reconstructed using filtered backprojection.

resultsOur current approach removes metal from the projections, which is robust to FOV truncation during imaging acquisition. In case of FOV truncation, the method outperformed the two-pass reconstruction method. The proposed method using DE renders better accuracy in metal segmentation than the MRF method and single-energy method, which were prone to false-positive errors that cause additional streaks. For the liver steering phantom, the average spatial nonuniformity was reduced from 0.127 in uncorrected images to 0.086 using a standard two-pass reconstruction and to 0.077 using the proposed method. For the cadaver head, the average standard deviation within selected soft tissue regions (

conclusionsWe proposed a MAR method that directly detects metal in the projection domain using DE imaging, which is robust to truncation and superior to that of single-energy imaging. The method requires only a single-pass reconstruction that substantially reduces processing time compared with the standard two-pass metal reduction method.

Indexed as

ArtifactsImage Processing, Computer-AssistedAlgorithmsCone-Beam Computed TomographyPhantoms, ImagingRadiographycone-beam CTdual-layerflat panel detectormaterial decompositionmetal artifact

Identifiers

PMID34374461
PMCPMC8665899

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.