ArticleMagnetic resonance in medicine2022
Quantitative time-of-flight MR angiography for simultaneous luminal and hemodynamic evaluation of the intracranial arteries.
Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Estimation of Blood Velocity from TOF-MRA Arterial Centerlines: Theory, Simulation, and Inverse Solution.Bioengineering (Basel, Switzerland) · 2026Article
- Jointly Learned 3D Non-Cartesian Sampling With Wave Encoding and Reconstruction for Neurovascular Phase Contrast MRI.Magnetic resonance in medicine · 2026Article
- Evaluation of Posture-Dependent Signal Intensity and Contrast Alterations in Low-Field Brain Magnetic Resonance Imaging.Diagnostics (Basel, Switzerland) · 2026Article
- Cellular Mechanisms Underlying Endothelial and Histopathological Alterations Induced by Cerebral Angiography.Journal of clinical medicine · 2026Review
- Simultaneous Luminal and Hemodynamic Evaluation of the Cervical Arteries Using Nonenhanced 3D Quantitative Quiescent-Interval Slice-Selective Magnetic Resonance Angiography.Journal of magnetic resonance imaging : JMRI · 2025Article
- Spiral time-of-flight magnetic resonance angiography for intracranial vascular imaging: performance compared to conventional Cartesian angiogram.Quantitative imaging in medicine and surgery · 2024Article
- Intracranial arterial flow velocity mapping in quantitative time-of-flight MR angiography using deep machine learning.Magnetic resonance imaging · 2023Article
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Abstract
purposeTo report a quantitative time-of-flight (qTOF) MRA technique for simultaneous luminal and hemodynamic evaluation of the intracranial arteries.
methodsImplemented using a thin overlapping slab 3D stack-of-stars based 3-echo FLASH readout, qTOF was tested in a flow phantom and for imaging the intracranial arteries of 10 human subjects at 3 Tesla. Display of the intracranial arteries with qTOF was compared to resolution-matched and scan time-matched standard Cartesian 3D time-of-flight (TOF) MRA, whereas quantification of mean blood flow velocity with qTOF, done using a computer vision-based inter-echo image analysis procedure, was compared to 3D phase contrast MRA. Arterial-to-background contrast-to-noise ratio was measured, and intraclass correlation coefficient was used to evaluate agreement of flow velocities.
resultsFor resolution-matched protocols of similar scan time, qTOF portrayed the intracranial arteries with good morphological correlation with standard Cartesian TOF, and both techniques provided superior contrast-to-noise ratio and arterial delineation compared to phase contrast (20.6 ± 3.0 and 37.8 ± 8.7 vs. 11.5 ± 2.2, P < .001, both comparisons). With respect to phase contrast, qTOF showed excellent agreement for measuring mean flow velocity in the flow phantom (intraclass correlation coefficient = 0.981, P < .001) and good agreement in the intracranial arteries (intraclass correlation coefficient = 0.700, P < .001). Stack-of-stars data sampling used with qTOF eliminated oblique in-plane flow misregistration artifacts that were seen with standard Cartesian TOF.
conclusionqTOF is a new 3D MRA technique for simultaneous luminal and hemodynamic evaluation of the intracranial arteries that provides significantly greater contrast-to-noise ratio efficiency than phase contrast and eliminates misregistration artifacts from oblique in-plane blood flow that occur with standard 3D TOF.
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