Trial reportEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2021
Prediction of radial crossover in acute coronary syndromes: derivation and validation of the MATRIX score.
Trial report in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 25 citations in OpenAlex.
- Predictors of a prolonged puncture-wire time in patients with ST-Elevation Myocardial Infarction (STEMI).BMC cardiovascular disorders · 2026Article
- Retrospective Analysis of Angiographic Radial Artery Spasm Predictors.Life (Basel, Switzerland) · 2025Article
- Procedural and Antithrombotic Therapy Optimization in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A Narrative Review.Journal of cardiovascular development and disease · 2025Review
- Impact of Anthropometric Measures on Distal vs Conventional Radial Access for Percutaneous Coronary Procedures.JACC. Advances · 2025Article
- Patient Characteristics and Outcomes of Radial to Femoral Access-Site Crossover.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Radial Artery Spasm-A Review on Incidence, Prevention and Treatment.Diagnostics (Basel, Switzerland) · 2024Review
- First application of the distal radial approach for severe mechanical surgical aortic valve paravalvular leak transcatheter closure with a double vascular plug: a case report.European heart journal. Case reports · 2024Article
- Assessment and Management of Older Adults Undergoing PCI, Part 1: AJACC. Advances · 2023Article
- Safety and efficacy of coronary angiography and percutaneous coronary intervention via distal transradial artery access in the anatomical snuffbox: a single-centre prospective cohort study using a propensity score method.BMC cardiovascular disorders · 2022Article
- Minimizing Guidewire Unwilling Passage and Related Perforation During Transradial Procedures: Prevention Is Better Than Cure.Frontiers in cardiovascular medicine · 2022Article
- Radial first, but not radial only.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Article
- Impact of anemia on in-stent restenosis after percutaneous coronary intervention.BMC cardiovascular disorders · 2021Article
- Association between the triglyceride glucose index and coronary collateralization in coronary artery disease patients with chronic total occlusion lesions.Lipids in health and disease · 2021Observational
Corrections and comments
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Authors and funding
23 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe radial artery is recommended by international guidelines as the default vascular access in patients with acute coronary syndromes (ACS) managed invasively. However, crossover from radial to femoral access is required in 4-10% of cases and has been associated with worse outcomes. No standardised algorithm exists to predict the risk of radial crossover.
aimsWe sought to derive and externally validate a risk score to predict radial crossover in patients with ACS managed invasively.
methodsThe derivation cohort consisted of 4,197 patients with ACS undergoing invasive management via the randomly allocated radial access from the MATRIX trial. Using logistic regression, we selected predictors of radial crossover and developed a numerical risk score. External validation was accomplished among 3,451 and 491 ACS patients managed invasively and randomised to radial access from the RIVAL and RIFLE-STEACS trials, respectively.
resultsThe MATRIX score (age, height, smoking, renal failure, prior coronary artery bypass grafting, ST-segment elevation myocardial infarction, Killip class, radial expertise) showed a c-index for radial crossover of 0.71 (95% CI: 0.67-0.75) in the derivation cohort. Discrimination ability was modest in the RIVAL (c-index: 0.64; 95% CI: 0.59-0.67) and RIFLE-STEACS (c-index: 0.66; 95% CI: 0.57-0.75) cohorts. A cut-off of ≥41 points was selected to identify patients at high risk of radial crossover.
conclusionsThe MATRIX score is a simple eight-item risk score which provides a standardised tool for the prediction of radial crossover among patients with ACS managed invasively. This tool can assist operators in anticipating and better addressing difficulties related to transradial procedures, potentially improving outcomes.
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