Stereoselective Installation of Five Contiguous Stereogenic Centers in a Double Aldol-Tishchenko Cascade and Evaluation of the Key Transition State through DFT Calculation.

Pamela Mackey, Aneta Turlik, Kaori Ando, Mark E Light, K N Houk, Gerard P McGlacken

Open access · hybridAbstract read

In one paragraph

Article in Organic letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.7field-weighted citation impact, top 36% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Pamela MackeySchool of Chemistry and Analytical and Biological Chemistry Research Facility, University College Cork, Cork, Ireland.

Aneta TurlikDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States.

Kaori AndoDepartment of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Yanagido 1-1, Gifu 501-1193, Japan.ORCID 0000-0001-5345-2754

Mark E LightUniversity of Southampton, Chemistry Department, University Road, Southampton SO17 1BJ, United Kingdom.

K N HoukDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, United States.ORCID 0000-0002-8387-5261

Gerard P McGlackenSchool of Chemistry and Analytical and Biological Chemistry Research Facility, University College Cork, Cork, Ireland.ORCID 0000-0002-7821-0804

University College Cork · IEUniversity of California, Los Angeles · USGifu University · JPUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The stereoselective formation of 5 contiguous chiral centers in a single pot reaction is demonstrated using an aldol, aldol-Tishchenko reaction of

Identifiers

PMID34374288

DOI10.1021/acs.orglett.1c02179

PMCPMC8383304

OpenAlexW3193180621

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.