Evidence map›Paper›PMID 34374148›Full record

ReviewAmerican journal of human biology : the official journal of the Human Biology Council2022

Current and future applications of biomarkers in samples collected through minimally invasive methods for cancer medicine and population-based research.

Alicia M DeLouize, Geeta Eick, Sana D Karam, J Josh Snodgrass

Abstract readReview
In one paragraph

Review in American journal of human biology : the official journal of the Human Biology Council, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alicia M DeLouizeDepartment of Anthropology, University of Oregon, Eugene, Oregon, USA.ORCID 0000-0002-9045-6428
Geeta EickDepartment of Anthropology, University of Oregon, Eugene, Oregon, USA.ORCID 0000-0001-7512-3265
Sana D KaramDepartment of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado, USA.
J Josh SnodgrassDepartment of Anthropology, University of Oregon, Eugene, Oregon, USA.ORCID 0000-0002-7021-777X

Funding

Tackling Treg mediated resistance to radiation and anti-PDL1 in HNSCCsR01DE028529 · NIDCR · WASHINGTON UNIVERSITY · PI SANA D KARAM · 2019 to 2026
$3.7M
Role of EphB4-ephrin-B2 interaction in regulating crosstalk between cancer cell and vascular tumor microenvironment in head and neck cancerR01DE028282 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI KARAM, SANA D · 2019 to 2023
$2.4M
NIDCR NIH HHS R01 DE028282NIDCR NIH HHS R01 DE028529
6 · The paper itself

Abstract

Despite advances in cancer medicine and research, invasive and potentially risky procedures such as biopsies, venous blood tests, imaging, colonoscopy, and pap smear tests are still primarily used for screening, staging, and assessing response to therapy. The development and interdisciplinary use of biomarkers from urine, feces, saliva, scent, and capillary blood collected with minimally invasive methods represents a potential opportunity for integration with biomarker analysis for cancers, both in clinical practice (e.g., in screening, treatment, and disease monitoring, and improved quality of life for patients) and population-based research (e.g., in epidemiology/public health, studies of social and environmental determinants, and evolutionary medicine). In this article, we review the scientific rationale, benefits, challenges, and potential opportunities for measuring cancer-related biomarkers in samples collected through minimally invasive methods.

Indexed as

NeoplasmsQuality of LifeBiomarkersBiomarkers, TumorFemaleHumansMass ScreeningSalivaBiomarkersBiomarkers, Tumor

Identifiers

PMID34374148
PMCPMC9894104

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.