Evidence map›Paper›PMID 34374094›Full record

ArticleClinical cardiology2021

The impact of atrial mechanical function on age-dependent presentation of neurocardiogenic syncope.

Melani Sotiriadou, Christodoulos E Papadopoulos, Antonios P Antoniadis, Panagiotis Roumelis, Stavros Vergopoulos, Periklis Konstantinidis, Efstathios D Pagourelias, Stergios Tzikas, Nikolaos Fragakis, Vassilios Vassilikos

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Article in Clinical cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Melani SotiriadouThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.
Christodoulos E PapadopoulosThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.
Antonios P AntoniadisThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.
Panagiotis RoumelisThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.
Stavros VergopoulosThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.
Periklis KonstantinidisThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.
Efstathios D PagoureliasThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.
Stergios TzikasThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.
Nikolaos FragakisThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-7158-4950
Vassilios VassilikosThird Department of Cardiology, Hippokration General Hospital, Aristotle University Medical School, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe contribution of atrial and ventricular function in neurocardiogenic syncope (NCS) pathophysiology is elusive. HYPOTHESIS: We assessed the influence of echocardiographic properties to the age of presentation and NCS recurrences.

methodsWe assigned 124 patients with symptoms suggesting NCS, to those with syncope initiation at age <35 (group A, n = 56) and >35 years (group B, n = 68). Echocardiographic indices were measured before head-up tilt test (HUTT).

resultsA total of 55 had positive HUTT (44%) with a trend favoring group A (p = .08). Group A exhibited lower left atrial (LA) volume index (17 ± 6 vs. 22 ± 11 ml/m

conclusionsPatients with younger age of NCS onset and more syncopal recurrences manifest smaller LA and RA dimensions with distinct patterns of systolic and diastolic function and better LA reservoir and contraction properties. These findings may indicate an increased susceptibility to preload reduction, thereby triggering the NCS mechanism.

Indexed as

Syncope, VasovagalAtrial Function, LeftAtrial Function, RightEchocardiographyHeart AtriaHumanshead-up tilt testleft atrial strainleft atrial strain rateleft ventricular diastolic functionneurocardiogenic syncoperight atrial ejection fraction

Identifiers

PMID34374094
PMCPMC8495094

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.