Evidence map›Paper›PMID 34373987›Full record

Trial reportAIDS and behavior2022

Water Insecurity is Associated with Lack of Viral Suppression and Greater Odds of AIDS-Defining Illnesses Among Adults with HIV in Western Kenya.

Jason M Nagata, Joshua D Miller, Craig R Cohen, Edward A Frongillo, Elly Weke, Rachel Burger, Pauline Wekesa, Lila A Sheira, A Rain Mocello, Phelgona Otieno and 4 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02815579 (Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02815579 nacompletednot on this map

Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2019Enrolled746ConditionsHIVArmsShamba Maisha Intervention
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Interacting Water Insecurity and Food Insecurity: Recent Advances in Theory and Application.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Jason M NagataDepartment of Pediatrics, University of California, 550 16th Street, Box 0110, San Francisco, CA, 94158, USA. jason.nagata@ucsf.edu.ORCID http://orcid.org/0000-0002-6541-0604
Joshua D MillerDepartment of Nutrition, University of North Carolina at Chapel Hill , Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-2171-856X
Craig R CohenDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, USA.
Edward A FrongilloDepartment of Health Promotion, Education, and Behavior, University of South Carolina, Columbia, SC, USA.
Elly WekeCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Rachel BurgerDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, USA.
Pauline WekesaCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Lila A SheiraDepartment of Medicine, University of California, San Francisco, CA, USA.
A Rain MocelloDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, USA.
Phelgona OtienoCentre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Lisa M ButlerInstitute for Collaboration On Health, Intervention and Policy, University of Connecticut, Storrs, CT, USA.
Elizabeth A BukusiDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, USA.
Sheri D WeiserDepartment of Medicine, University of California, San Francisco, CA, USA.
Sera L YoungDepartment of Anthropology, Northwestern University, Evanston, IL, USA.ORCID http://orcid.org/0000-0002-1763-1218
University of California, San Francisco · USKenya Medical Research Institute · KENorthwestern University · USUniversity of Connecticut · USUniversity of North Carolina at Chapel Hill · USUniversity of South Carolina · US

Funding

Agricultural intervention for food security and HIV healthoutcomes in KenyaR01MH107330 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COHEN, CRAIG R, WEISER, SHERI DAWN · 2015 to 2019
$4.7M
Sustainable Development for Improved HIV Health and Prevention in Kenya (SD4H-Kenya)D43TW011306 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUKUSI, ELIZABETH ANNE, COHEN, CRAIG R · 2020 to 2024
$1.9M
FIC NIH HHS D43 TW011306NIMH NIH HHS R01 MH107330
6 · The paper itself

Abstract

Reliable access to safe and acceptable water in sufficient quantities (i.e., water security) is important for medication adherence and limiting pathogen exposure, yet prior studies have only considered the role of food security as a social determinant of HIV-related health. Therefore, the objective of this analysis was to assess the relationships between household water insecurity and HIV-related outcomes among adults living with HIV in western Kenya (N = 716). We conducted a cross-sectional analysis of baseline data from Shamba Maisha (NCT02815579), a cluster randomized controlled trial of a multisectoral agricultural and asset loan intervention. Baseline data were collected from June 2016 to December 2017. We assessed associations between water insecurity and HIV-related outcomes, adjusting for clinical and behavioral confounders, including food insecurity. Each five-unit higher household water insecurity score (range: 0-51) was associated with 1.21 higher odds of having a viral load ≥ 1000 copies/mL (95% CI 1.07, 1.36) and 1.26 higher odds of AIDS-defining illness (95% CI 1.11, 1.42). Household water insecurity was not associated with CD4 cell count (B: 0.27; 95% CI -3.59, 13.05). HIV treatment and support programs should consider assessing and addressing water insecurity in addition to food insecurity to optimize HIV outcomes.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsCross-Sectional StudiesFood SupplyHumansKenyaWater InsecurityAIDSFood insecurityHuman immunodeficiency virusKenyaWater insecurity

Identifiers

PMID34373987
PMCPMC8813828
OpenAlexW3191757819

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.