Evidence map›Paper›PMID 34373818›Full record

ArticleCureus2021

Phlegmasia Cerulea Dolens: A New Perspective on Management.

Harry G Sequeira Gross, Yomary Jimenez, Camelia Ciobanu, Kidist Tarekegn, Ana Colon Ramos, Jeffrey Lazar

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  3. A blistering variant of phlegmasia cerulea dolens from underlying squamous cell lung cancer.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Harry G Sequeira GrossInternal Medicine, St. Barnabas Hospital, The Bronx, USA.
Yomary JimenezMedicine, St. Barnabas Hospital, The Bronx, USA.
Camelia CiobanuMedicine, St. Barnabas Hospital, The Bronx, USA.
Kidist TarekegnInternal Medicine, St. Barnabas Hospital, The Bronx, USA.
Ana Colon RamosInternal Medicine, St. Barnabas Hospital, The Bronx, USA.
Jeffrey LazarEmergency Medicine, St. Barnabas Hospital Health System, The Bronx, USA.
St. Barnabas Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a case of phlegmasia cerulea dolens (PCD) with unexpected but complete resolution of symptoms with short-term administration of heparin products, despite falling into category IIb according to the Rutherford limb ischemia scale, which regularly requires aggressive surgical intervention. We present a case of a 58-year-old Hispanic female with a past medical history of gastritis who arrived at the emergency room (ER) with acute onset severe pain on the left leg associated with discoloration of the leg. The patient was quickly diagnosed with PCD affecting the left lower extremity, which quickly resolved after administration of heparin infusion for one hour, despite the degree of limb ischemia. There is no consensus for the treatment of this condition. The most interesting feature of this case is the prompt resolution of symptoms with short-term administration of anticoagulation with total resolution without the need for thrombolysis or thrombectomy. This may suggest that prompt pharmacologic treatment in patients eligible for anticoagulation may successfully restore venous flow negating the need for further intervention.

Indexed as

case presentationnew perspectivephlegmasia cerulea dolensrare caseunexpected outcome

Identifiers

PMID34373818
PMCPMC8349176
OpenAlexW3181956730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.