Evidence map›Paper›PMID 34373761›Full record

ArticleTheranostics2021

Probiotics Stimulate Bone Formation in Obese Mice via Histone Methylations.

Jyotirmaya Behera, Jessica Ison, Michael J Voor, Neetu Tyagi

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

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  6. The gut-bone-inflammation axis: intestinal barrier disruption as a central driver of osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jyotirmaya BeheraBone Biology Laboratory, Department of Physiology, School of Medicine, University of Louisville, Louisville, KY 40202 USA.
Jessica IsonBone Biology Laboratory, Department of Physiology, School of Medicine, University of Louisville, Louisville, KY 40202 USA.
Michael J VoorDepartment of Orthopaedic Surgery, School of Medicine, University of Louisville, Louisville, KY 40202 USA.
Neetu TyagiBone Biology Laboratory, Department of Physiology, School of Medicine, University of Louisville, Louisville, KY 40202 USA.
University of Louisville · US

Funding

Mitigating mitochondrial epigenetics in bone remodeling by hydrogen sulfideR01AR067667 · NIAMS · UNIVERSITY OF LOUISVILLE · PI TYAGI, NEETU, TYAGI, SURESH C. · 2015 to 2019
$2.5M
NIAMS NIH HHS R01 AR067667
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBone and BonesBone DevelopmentDiet, High-FatDysbiosisEpigenesis, GeneticFemaleGastrointestinal MicrobiomeHistonesInflammationInsulin ResistanceMethylationMiceMice, Inbred C57BLMice, ObeseMitochondriaHistonesRNA, Ribosomal, 16Sbone lossgut microbiotahistone methylationmitochondrial biogenesisosteoblasts mineralization

Identifiers

PMID34373761
PMCPMC8344023
OpenAlexW3183496115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.