Evidence map›Paper›PMID 34373759›Full record

ArticleTheranostics2021

Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota.

Lingjun Tong, Haining Hao, Zhe Zhang, Youyou Lv, Xi Liang, Qiqi Liu, Tongjie Liu, Pimin Gong, Lanwei Zhang, Fangfang Cao and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 146 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
146citing papers in PubMed, 4 pooled it
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

146 citing papers in PubMed, 4 syntheses or guidelines pooled it, 298 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Article
  7. Article
  8. Extracellular Vesicles Derived fromNanomaterials (Basel, Switzerland) · 2026
    Article
  9. Review
  10. Article
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86 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Lingjun TongCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Haining HaoCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Zhe ZhangCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Youyou LvCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Xi LiangCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Qiqi LiuCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Tongjie LiuCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Pimin GongCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Lanwei ZhangCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Fangfang CaoDepartments of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119074, Singapore.
Giorgia PastorinDepartment of Pharmacy, Faculty of Science, National University of Singapore, Singapore 117543, Singapore.
Chuen Neng LeeDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228, Singapore.
Xiaoyuan ChenDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228, Singapore.
Jiong-Wei WangDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228, Singapore.
Huaxi YiCollege of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao 266003, P. R. China.
Ocean University of China · CNNational University of Singapore · SGChina Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsChinaColitisColitis, UlcerativeColonCytokinesDisease Models, AnimalExtracellular VesiclesGastrointestinal MicrobiomeInflammatory Bowel DiseasesIntestinal MucosaIntestinesMaleMiceMice, Inbred C57BLMilkCytokinesNF-kappa BRNA, Ribosomal, 16SExtracellular vesiclesgut microbiomeintestinal immunityTreg/Th17 cell balanceulcerative colitis

Identifiers

PMID34373759
PMCPMC8344018
OpenAlexW3183532060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.