Evidence map›Paper›PMID 34373754›Full record

ArticleTheranostics2021

Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-β signaling.

Qian Wu, Xuemeng Miao, Jingjing Zhang, Ludan Xiang, Xiuchun Li, Xiaomei Bao, Siyu Du, Mianxian Wang, Shuangda Miao, Yiren Fan and 13 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
8.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 109 citations in OpenAlex.

  1. The Hippo signalling pathway and its impact on eye diseases.Journal of cellular and molecular medicine · 2024
    Pooled it
  2. SNX3 exacerbates hepatic fibrosis by amplifying TGF-Acta pharmaceutica Sinica. B · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 2 institutions in 1 country.

Qian WuSchool of pharmacy and Holistic Integrative Pharmacy Institutes, Hangzhou Normal University, Hangzhou, Zhejiang, 311121, China.
Xuemeng MiaoSchool of Mental Health, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Jingjing ZhangSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Ludan XiangSchool of Mental Health, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Xiuchun LiThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Xiaomei BaoSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Siyu DuSchool of Mental Health, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Mianxian WangSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Shuangda MiaoThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Yiren FanSchool of Mental Health, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Wei WangSchool of Mental Health, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Xingxing XuSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Xiya ShenSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Danlu YangSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Xiwu WangSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Yuanyuan FangSchool of Mental Health, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Lixin HuSchool of Mental Health, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Xuyi PanThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Haoru DongThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Hui WangThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Ying WangPhase I Clinical Research Center, Zhejiang Provincial People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310053, China.
Jia LiThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Zhihui HuangSchool of pharmacy and Holistic Integrative Pharmacy Institutes, Hangzhou Normal University, Hangzhou, Zhejiang, 311121, China.
Wenzhou Medical University · CNFirst Affiliated Hospital of Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAstrocytesDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalFemaleMiceMice, Inbred C57BLMultiple SclerosisNeuroinflammatory DiseasesOptic NerveOptic NeuritisRetinaRetinal Ganglion CellsSignal TransductionTransforming Growth Factor betaYAP-Signaling ProteinsTransforming Growth Factor betaYap1 protein, mouseYAP-Signaling Proteinsastrocytesneuroinflammationoptic neuritisTGF-β1YAP

Identifiers

PMID34373754
PMCPMC8344002
OpenAlexW3188247743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.