Evidence map›Paper›PMID 34373529›Full record

ArticleScientific reports2021

In vivo exploration of synaptic projections in frontotemporal dementia.

Eric Salmon, Mohamed Ali Bahri, Alain Plenevaux, Guillaume Becker, Alain Seret, Emma Delhaye, Christian Degueldre, Evelyne Balteau, Christian Lemaire, André Luxen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Associations between fluid biomarkers and PET imaging ([11C]UCB-J) of synaptic pathology in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  2. Radiopharmaceuticals and their applications in medicine.Signal transduction and targeted therapy · 2025
    Review
  3. Synaptic changes in psychiatric and neurological disorders: state-of-the art of in vivo imaging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  4. Review
  5. Article
  6. SV2A PET imaging in human neurodegenerative diseases.Frontiers in aging neuroscience · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Imaging of Synaptic Density in Neurodegenerative Disorders.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Eric SalmonGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium. eric.salmon@ulg.ac.be.
Mohamed Ali BahriGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
Alain PlenevauxGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
Guillaume BeckerGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
Alain SeretGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
Emma DelhayeGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
Christian DegueldreGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
Evelyne BalteauGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
Christian LemaireGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
André LuxenGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
Christine BastinGIGA Cyclotron Research Centre, University of Liège, B30 Sart Tilman, 4000, Liège, Belgium.
University of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this exploratory research is to provide data on synaptopathy in the behavioral variant of frontotemporal dementia (bvFTD). Twelve patients with probable bvFTD were compared to 12 control participants and 12 patients with Alzheimer's disease (AD). Loss of synaptic projections was assessed with [

Indexed as

AgedAlzheimer DiseaseFemaleFrontotemporal DementiaHippocampusHumansMaleMemory DisordersMemory, EpisodicNeuropsychological TestsParahippocampal GyrusPrefrontal CortexSynapses

Identifiers

PMID34373529
PMCPMC8352914
OpenAlexW3187315806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.