Evidence map›Paper›PMID 34373475›Full record

ArticleScientific reports2021

External assessment of the EUROMACS right-sided heart failure risk score.

Hirak Shah, Thomas Murray, Jessica Schultz, Ranjit John, Cindy M Martin, Thenappan Thenappan, Rebecca Cogswell

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hirak ShahDepartment of Medicine, Division of Cardiology, University of Minnesota, 401 East River Parkway, Variety Club Research Center (VCRC), 1st Floor - Suite 131, Minneapolis, MN, 55455, USA.
Thomas MurrayDivision of Biostatistics, University of Minnesota, Minneapolis, MN, USA.
Jessica SchultzDepartment of Medicine, Division of Cardiology, University of Minnesota, 401 East River Parkway, Variety Club Research Center (VCRC), 1st Floor - Suite 131, Minneapolis, MN, 55455, USA.
Ranjit JohnDepartment of Cardiothoracic Surgery, Division of Surgery, University of Minnesota, Minneapolis, MN, USA.
Cindy M MartinDepartment of Medicine, Division of Cardiology, University of Minnesota, 401 East River Parkway, Variety Club Research Center (VCRC), 1st Floor - Suite 131, Minneapolis, MN, 55455, USA.
Thenappan ThenappanDepartment of Medicine, Division of Cardiology, University of Minnesota, 401 East River Parkway, Variety Club Research Center (VCRC), 1st Floor - Suite 131, Minneapolis, MN, 55455, USA.
Rebecca CogswellDepartment of Medicine, Division of Cardiology, University of Minnesota, 401 East River Parkway, Variety Club Research Center (VCRC), 1st Floor - Suite 131, Minneapolis, MN, 55455, USA. cogsw014@umn.edu.
University of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The EUROMACS Right-Sided Heart Failure Risk Score was developed to predict right ventricular failure (RVF) after left ventricular assist device (LVAD) placement. The predictive ability of the EUROMACS score has not been tested in other cohorts. We performed a single center analysis of a continuous-flow (CF) LVAD cohort (n = 254) where we calculated EUROMACS risk scores and assessed for right ventricular heart failure after LVAD implantation. Thirty-nine percent of patients (100/254) had post-operative RVF, of which 9% (23/254) required prolonged inotropic support and 5% (12/254) required RVAD placement. For patients who developed RVF after LVAD implantation, there was a 45% increase in the hazards of death on LVAD support (HR 1.45, 95% CI 0.98-2.2, p = 0.066). Two variables in the EUROMACS score (Hemoglobin and Right Atrial Pressure to Pulmonary Capillary Wedge Pressure ratio) were not predictive of RVF in our cohort. Overall, the EUROMACS score had poor external discrimination in our cohort with area under the curve of 58% (95% CI 52-66%). Further work is necessary to enhance our ability to predict RVF after LVAD implantation.

Indexed as

AgedCohort StudiesFemaleHeart-Assist DevicesHeart FailureHeart VentriclesHumansMaleMiddle AgedProsthesis ImplantationPulmonary Wedge PressureRisk AssessmentRisk FactorsVentricular Dysfunction, Right

Identifiers

PMID34373475
PMCPMC8352910
OpenAlexW3187528563

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.