Evidence map›Paper›PMID 34373462›Full record

ArticleNPJ microgravity2021

Contractile behavior of the gastrocnemius medialis muscle during running in simulated hypogravity.

Charlotte Richter, Bjoern Braunstein, Benjamin Staeudle, Julia Attias, Alexander Suess, Tobias Weber, Katya N Mileva, Joern Rittweger, David A Green, Kirsten Albracht

Open access · goldAbstract read
In one paragraph

Article in NPJ microgravity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Charlotte RichterDepartment of Medical Engineering and Technomathematics, University of Applied Sciences Aachen, Aachen, Germany. cr.publications@planet3.de.ORCID http://orcid.org/0000-0002-8910-8602
Bjoern BraunsteinGerman Sport University Cologne, Institute of Movement and Neurosciences, Cologne, Germany.ORCID http://orcid.org/0000-0002-5173-8916
Benjamin StaeudleDepartment of Medical Engineering and Technomathematics, University of Applied Sciences Aachen, Aachen, Germany.
Julia AttiasKing's College London, Centre of Human and Applied Physiological Sciences, London, UK.ORCID http://orcid.org/0000-0003-3420-7977
Alexander SuessEuropean Astronaut Centre (EAC), European Space Agency, Space Medicine Team (HRE-OM), Cologne, Germany.
Tobias WeberEuropean Astronaut Centre (EAC), European Space Agency, Space Medicine Team (HRE-OM), Cologne, Germany.ORCID http://orcid.org/0000-0002-3015-3468
Katya N MilevaLondon South Bank University, School of Applied Sciences, London, UK.ORCID http://orcid.org/0000-0002-5412-8566
Joern RittwegerInstitute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.ORCID http://orcid.org/0000-0002-2223-8963
David A GreenKing's College London, Centre of Human and Applied Physiological Sciences, London, UK.ORCID http://orcid.org/0000-0001-8634-8769
Kirsten AlbrachtDepartment of Medical Engineering and Technomathematics, University of Applied Sciences Aachen, Aachen, Germany.ORCID http://orcid.org/0000-0002-4271-2511
German Sport University Cologne · DEEuropean Astronaut Centre · DEKing's College London · GBLondon South Bank University · GBUniversity of Cologne · DE

Funding

Bundesministerium für Wirtschaft und Energie (Federal Ministry for Economic Affairs and Energy) 50WB1728
6 · The paper itself

Abstract

Vigorous exercise countermeasures in microgravity can largely attenuate muscular degeneration, albeit the extent of applied loading is key for the extent of muscle wasting. Running on the International Space Station is usually performed with maximum loads of 70% body weight (0.7 g). However, it has not been investigated how the reduced musculoskeletal loading affects muscle and series elastic element dynamics, and thereby force and power generation. Therefore, this study examined the effects of running on the vertical treadmill facility, a ground-based analog, at simulated 0.7 g on gastrocnemius medialis contractile behavior. The results reveal that fascicle-series elastic element behavior differs between simulated hypogravity and 1 g running. Whilst shorter peak series elastic element lengths at simulated 0.7 g appear to be the result of lower muscular and gravitational forces acting on it, increased fascicle lengths and decreased velocities could not be anticipated, but may inform the development of optimized running training in hypogravity. However, whether the alterations in contractile behavior precipitate musculoskeletal degeneration warrants further study.

Identifiers

PMID34373462
PMCPMC8352871
OpenAlexW3189307195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.