Evidence map›Paper›PMID 34373449›Full record

ArticleCell death & disease2021

FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation.

Lan Xu, Weiwei Xu, Duan Li, Xiaoxia Yu, Fei Gao, Yingying Qin, Yajuan Yang, Shidou Zhao

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

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  14. Review
  15. Sex body: A nest of protein mixture.Frontiers in cell and developmental biology · 2023
    Review
  16. Transcription-replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Review
  18. Focal Point of Fanconi Anemia Signaling.International journal of molecular sciences · 2021
    Review
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lan XuCenter for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Weiwei XuCenter for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Duan LiCenter for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Xiaoxia YuCenter for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Fei GaoState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.ORCID http://orcid.org/0000-0002-4029-6411
Yingying QinCenter for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Yajuan YangCenter for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China. yangyajuan1991@163.com.ORCID http://orcid.org/0000-0002-4828-0967
Shidou ZhaoCenter for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.ORCID http://orcid.org/0000-0003-4722-1575
Shandong University · CNChinese Academy of Sciences · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 81771541National Natural Science Foundation of China (National Science Foundation of China) 81873823
6 · The paper itself

Abstract

FANCI is an essential component of Fanconi anemia pathway, which is responsible for the repair of DNA interstrand cross-links (ICLs). As an evolutionarily related partner of FANCD2, FANCI functions together with FANCD2 downstream of FA core complex. Currently, growing evidences showed that the essential role of FA pathway in male fertility. However, the underlying mechanisms for FANCI in regulating spermatogenesis remain unclear. In the present study, we found that the male Fanci

Indexed as

MeiosisSpermatogenesisAnimalsApoptosisCell DifferentiationEpigenesis, GeneticFanconi AnemiaGene DeletionHistonesInfertility, MaleLysineMaleMethylationMiceOrgan SpecificityProphaseHistonesLysineRNA, Messenger

Identifiers

PMID34373449
PMCPMC8353022
OpenAlexW3190266870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.