Evidence map›Paper›PMID 34373271›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2021

Use of fluorescence to visualize response to iloprost treatment for frostbite.

Mira MacLennan, Alexander Poole, Josianne Gauthier

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Frostbite treatment: a systematic review with meta-analyses.Scandinavian journal of trauma, resuscitation and emergency medicine · 2023
    Pooled it
  2. Synthesis of Protocols for Frostbite Care From the FROST Study Sites.Journal of burn care & research : official publication of the American Burn Association · 2026
    Observational
  3. Time to Thrombolytics and Tissue Salvage: Assessing Response Following Severe Frostbite Injury.Journal of burn care & research : official publication of the American Burn Association · 2025
    Article
  4. Iloprost for the treatment of frostbite: a scoping review.International journal of circumpolar health · 2023
    Article
  5. Review
4 · The record

Corrections and comments

  • Commented on by
    2021
5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Mira MacLennanDepartment of Surgery (MacLennan), McMaster University, Hamilton, Ont.; Harvard T.H. Chan School of Public Health (MacLennan), Boston, Mass.; Whitehorse General Hospital (Poole, Gauthier), Whitehorse, YT; Department of Surgery (Poole), Cumming School of Medicine, University of Calgary, Calgary, Alta.; University of Saskatchewan (Gauthier), Saskatoon, Sask. mira.maclennan@medportal.ca.
Alexander PooleDepartment of Surgery (MacLennan), McMaster University, Hamilton, Ont.; Harvard T.H. Chan School of Public Health (MacLennan), Boston, Mass.; Whitehorse General Hospital (Poole, Gauthier), Whitehorse, YT; Department of Surgery (Poole), Cumming School of Medicine, University of Calgary, Calgary, Alta.; University of Saskatchewan (Gauthier), Saskatoon, Sask.
Josianne GauthierDepartment of Surgery (MacLennan), McMaster University, Hamilton, Ont.; Harvard T.H. Chan School of Public Health (MacLennan), Boston, Mass.; Whitehorse General Hospital (Poole, Gauthier), Whitehorse, YT; Department of Surgery (Poole), Cumming School of Medicine, University of Calgary, Calgary, Alta.; University of Saskatchewan (Gauthier), Saskatoon, Sask.
Harvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Coloring AgentsFluorescenceFrostbiteHumansIloprostIndocyanine GreenMaleMiddle AgedOptical ImagingTreatment OutcomeVasodilator AgentsColoring AgentsIloprostIndocyanine GreenVasodilator Agents

Identifiers

PMID34373271
PMCPMC8367417
OpenAlexW3187629200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.