Evidence map›Paper›PMID 34372952›Full record

ArticleEpidemiology and infection2021

Serological and molecular detection of pathogenic

M Holzapfel, F Taraveau, Z Djelouadji

Abstract read
In one paragraph

Article in Epidemiology and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Seroprevalence of pathogenicFrontiers in veterinary science · 2024
    Review
  6. Evaluation ofJournal of feline medicine and surgery · 2023
    Article
  7. Pathogens (Basel, Switzerland) · 2022
    Article
  8. Host and Species-Specificities of Pattern Recognition Receptors Upon Infection WithFrontiers in cellular and infection microbiology · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

M HolzapfelUSC1233-INRA, Rongeurs Sauvages, Risque Sanitaire et Gestion des Populations, Établissement VetAgro Sup, Campus vétérinaire de Lyon, Marcy l'Etoile, France.
F TaraveauUSC1233-INRA, Rongeurs Sauvages, Risque Sanitaire et Gestion des Populations, Établissement VetAgro Sup, Campus vétérinaire de Lyon, Marcy l'Etoile, France.
Z DjelouadjiUSC1233-INRA, Rongeurs Sauvages, Risque Sanitaire et Gestion des Populations, Établissement VetAgro Sup, Campus vétérinaire de Lyon, Marcy l'Etoile, France.ORCID 0000-0002-5793-5144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indian Ocean islands are endemic areas for human and animal leptospirosis. Maintenance host species for Leptospira spp. have still not been completely elucidated, and recently the role of cats (Felis catus) has been questioned. This cross-sectional study aims to determine whether cats are part of the maintenance community of different strains of Leptospira spp. in Reunion Island. The prevalence of Leptospira infection in an opportunistic sample of stray and domestic cats (n = 92) from Reunion Island has been studied using serological (microagglutination test) and molecular detection (polymerase chain reaction (PCR)). The results revealed a seroprevalence of 37.0% (34/92) (cut-off 1:40) without a significant difference in the living conditions of animals. The predominant serogroup was Icterohaemorrhagiae, but Ballum, Cynopteri and Australis were also detected. Using PCR, 28.6% (12/42) of stray cats were tested positive. Leptospiral DNA was detected in renal tissue, urine and blood of respectively 14.3% (6/42), 10.3% (4/39) and 11.9% (5/42) of stray cats, but 0% (0/3), 0% (0/50) and 0% (0/36) of domestic cats (P = non-applicable, P = 0,038, P = 0,058 respectively). Partial rrs gene (16S rRNA) sequencing identified Leptospira interrogans in all PCR-positive samples. Our study confirms that renal carriage and urinary shedding are possible, positioning cats, and especially stray cats as potential actors within the maintenance community of L. interrogans in Reunion Island.

Indexed as

AnimalsCat DiseasesCatsKidneyLeptospiraLeptospira interrogansLeptospirosisPetsReunionRNA, Ribosomal, 16SSeroepidemiologic StudiesZoonosesRNA, Ribosomal, 16SCatepidemiologyleptospirosispublic healthreservoir

Identifiers

PMID34372952
PMCPMC8569831

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.