Toxigenic

Sepideh Khodaparast, Ashraf Mohabati Mobarez, Nima Khoramabadi, Mohammad Vasei, Mehdi Saberifiroozi

Abstract read

In one paragraph

Article in Epidemiology and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sepideh KhodaparastDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.ORCID 0000-0002-3290-9265

Ashraf Mohabati MobarezDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.ORCID 0000-0002-1224-6134

Nima KhoramabadiDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Mohammad VaseiCell-based Therapies Research Centre, Digestive Disease Research Institute, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Mehdi SaberifirooziDigestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogenic hematopoietic stem cell transplant (HSCT) recipients are susceptible to any kind of infectious agents including Clostridium difficile. We studied 86 allogenic-HSCT patients who faced diarrhoea while receiving antibiotics. DNA from stool samples were explored for the presence of C. difficile toxin genes (tcdA; tcdB) by multiplex real-time PCR. Results showed nine toxigenic C. difficile amongst which seven were positive for both toxins and two were positive for tcdB. Six of toxigenic C. difficile organisms harbouring both toxin genes were also isolated by toxigenic culture. Clostridium difficile infection was controlled successfully with oral Metronidazole and Vancomycin in the confirmed infected patients.

Indexed as

Hematopoietic Stem Cell TransplantationAnti-Bacterial AgentsBacterial ProteinsClostridioides difficileClostridium InfectionsDiarrheaDNA, BacterialDrug Therapy, CombinationEnterotoxinsHumansMetronidazolePolymerase Chain ReactionTreatment OutcomeVancomycinAnti-Bacterial AgentsBacterial ProteinsDNA, BacterialEnterotoxinsMetronidazoleVancomycinClostridium difficilehematopoietic stem cell transplantreal-time PCR

Identifiers

PMID34372951

DOI10.1017/S095026882100162X

PMCPMC8697310

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.