Evidence map›Paper›PMID 34372928›Full record

ArticlePerioperative medicine (London, England)2021

The influence of fasting and carbohydrate-enriched drink administration on body water amount and distribution: a volunteer randomized study.

Jakub Kukliński, Karol P Steckiewicz, Bartosz Sekuła, Aleksander Aszkiełowicz, Radosław Owczuk

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Perioperative medicine (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04665349 (Effect of Fasting on the Non-invasive Measurement of the Body's Water Compartments), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04665349 nacompletednot on this map

Effect of Fasting on the Non-invasive Measurement of the Body's Water Compartments

TypeinterventionalSponsorMedical University of GdanskRan2019 to 2020Enrolled81ConditionsDehydration, Perioperative ComplicationArmsNutricia Pre-op, 400 milliliters, per os
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Perioperative carbohydrate loading in patients undergoing one-day surgery. A systematic review of randomized controlled trials.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jakub KuklińskiStudent Scientific Society, Department of Anesthesiology and Intensive Care, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland.ORCID https://orcid.org/0000-0002-1305-4767
Karol P SteckiewiczStudent Scientific Society, Department of Anesthesiology and Intensive Care, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland. karol.steckiewicz@gumed.edu.pl.ORCID http://orcid.org/0000-0002-5353-9849
Bartosz SekułaStudent Scientific Society, Department of Anesthesiology and Intensive Care, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland.ORCID https://orcid.org/0000-0001-5887-7436
Aleksander AszkiełowiczDepartment of Anesthesiology and Intensive Care, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland.ORCID https://orcid.org/0000-0002-6073-0588
Radosław OwczukDepartment of Anesthesiology and Intensive Care, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland.ORCID https://orcid.org/0000-0002-3441-5162
Gdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFasting prior to anesthesia is considered aspiration prophylaxis. However, prolonged food and drink restrictions may increase the risk of other complications. The aim of this study was to assess whether a carbohydrate-enriched drink (Nutricia™ preOp®), recommended by the enhanced recovery after surgery (ERAS) protocol, can improve body hydration in fasting healthy individuals.

methodsMeasurements were done with the bioelectric impedance analysis with a Fresenius body composition monitor. Body composition, total body water, water distribution, and hemodynamic parameters were measured at the beginning of the study and after 10 h and 12 h of fasting. Patients fasted for 10 h and then were divided into two groups: the control (n = 40) and the pre-op group (n = 41). The pre-op group received 400 mL of Nutricia™ preOp®, as suggested in the ERAS guidance. The two-tailed Student's t test was used to compare two groups with normally distributed data and homogenous variances; if variances were heterogeneous, Welch's test was used. The Mann-Whitney U test was used to compare two groups with non-normal data distribution. p < 0.05 was considered statistically significant.

resultsWe found no significant differences between the control and pre-op groups regarding body water distribution and body composition. We did not observe significant losses in the total body water after fasting. Also, blood pressure was not affected by fasting.

conclusionWe have proven that pre-op did not impact either body composition or body water.

trial registrationClinicalTrials.gov , NCT04665349 . Registered on 11 December 2020-retrospectively registered.

Indexed as

Bioelectrical impedance analysisDehydrationEnhanced recovery after surgery (ERAS)Extracellular waterFastingIntracellular waterPre-op, Perioperative patient managementTotal body water

Identifiers

PMID34372928
PMCPMC8353831
OpenAlexW3188218330

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.