Evidence map›Paper›PMID 34372906›Full record

ArticleTrials2021

Caudal epidural steroid injections versus selective nerve root blocks for single-level lumbar spinal stenosis: a study protocol for a randomized controlled trial.

Akram Osman, Wei Hu, Jianhua-Sun, Jing Li, Xiao Luo, Nianrong Han, Ehsan Abduhani, Zhenqiang Liu

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Akram OsmanThe Second Spine Department of the Fourth School of Clinical Medicine of Xinjiang Medical University, Spine Department of the First Affiliated Hospital of Shihezi University, Shihezi, China.
Wei HuThe Second Spine Department of the Fourth School of Clinical Medicine of Xinjiang Medical University, Spine Department of the First Affiliated Hospital of Shihezi University, Shihezi, China. realhuwei@163.com.
Jianhua-SunThe Second Spine Department of the Fourth School of Clinical Medicine of Xinjiang Medical University, Spine Department of the First Affiliated Hospital of Shihezi University, Shihezi, China.
Jing LiThe Second Spine Department of the Fourth School of Clinical Medicine of Xinjiang Medical University, Spine Department of the First Affiliated Hospital of Shihezi University, Shihezi, China.
Xiao LuoThe Second Spine Department of the Fourth School of Clinical Medicine of Xinjiang Medical University, Spine Department of the First Affiliated Hospital of Shihezi University, Shihezi, China.
Nianrong HanThe Second Spine Department of the Fourth School of Clinical Medicine of Xinjiang Medical University, Spine Department of the First Affiliated Hospital of Shihezi University, Shihezi, China.
Ehsan AbduhaniThe Second Spine Department of the Fourth School of Clinical Medicine of Xinjiang Medical University, Spine Department of the First Affiliated Hospital of Shihezi University, Shihezi, China.
Zhenqiang LiuThe Second Spine Department of the Fourth School of Clinical Medicine of Xinjiang Medical University, Spine Department of the First Affiliated Hospital of Shihezi University, Shihezi, China.
First Affiliated Hospital of Shihezi University Medical College · CNXinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLumbar spinal stenosis (LSS) is a common degenerative condition associated with old age. Its incidence continues to increase with the rapidly aging population in China. Treatment for LSS usually begins with conservative treatments, as some patients refuse surgical procedures or have surgery contraindications. Caudal epidural steroid injections (CESIs) and selective nerve root blocks (SNRBs) are two commonly used conservative treatments for LSS, which have proven to be effective at relieving LSS symptoms in many studies. However, there are no randomized controlled trials comparing these two procedures. We planned the first study to assess which one of these two procedures is more effective in treating LSS. We will compare the efficacy of these two treatment methods in terms of duration of symptom relief and recurrence rate. We hope our findings will help clinicians choose an optimal treatment for LSS patients. METHODS/

designWe plan to conduct a 1-year randomized controlled trial that will include a total of 76 subjects. They will be randomly divided into two groups: group A (patients will receive CESIs) and group B (patients will receive SNRBs). Two days before the procedure, we will assess these patients using the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale, Oswestry Disability Index (ODI), and numeric rating scale (NRS) for pain. One day, 2 weeks, 3 months, 6 months, and 1 year after the procedure, we will assess the condition of these patients again with the NRS and ODI. DISCUSSION: We hope our findings will lay the foundation for the design of further comprehensive studies and help clinicians make a choice between CESIs and SNRBs for LSS patients.

trial registrationChinese Clinical Trial Registry ChiCTR1900028038 . Registered on 8 December 2019.

Indexed as

Anesthesia, EpiduralNerve BlockSpinal StenosisAgedHumansInjections, EpiduralLumbar VertebraeRandomized Controlled Trials as TopicSteroidsTreatment OutcomeSteroidsCaudal epidural steroid injectionsLumbar spinal stenosisRandomized controlled trialSelective nerve root blocks

Identifiers

PMID34372906
PMCPMC8351452
OpenAlexW3190231711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.