Evidence map›Paper›PMID 34372879›Full record

Observational studyAIDS research and therapy2021

The impact of gender and the social determinants of health on the clinical course of people living with HIV in Myanmar: an observational study.

Phyo Pyae Nyein, Eithandee Aung, Ne Myo Aung, Mar Mar Kyi, Mark Boyd, Kyaw Swar Lin, Josh Hanson

Abstract readObservational Study
In one paragraph

Observational study in AIDS research and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. FibroScanMicroorganisms · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Phyo Pyae NyeinMingaladon Specialist Hospital, Mingaladon Township, Yangon, Myanmar.
Eithandee AungThe Kirby Institute, University of New South Wales Sydney, Sydney, Australia.
Ne Myo AungUniversity of Medicine 2, North Okkalapa Township, Yangon, Myanmar.
Mar Mar KyiUniversity of Medicine 2, North Okkalapa Township, Yangon, Myanmar.
Mark BoydFaculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.
Kyaw Swar LinMingaladon Specialist Hospital, Mingaladon Township, Yangon, Myanmar.
Josh HansonUniversity of Medicine 2, North Okkalapa Township, Yangon, Myanmar. jhanson@kirby.unsw.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a growing recognition of the impact of gender and the social determinants of health on the clinical course of people living with HIV (PLHIV). However, the relative contribution of these factors to clinical outcomes of PLHIV is incompletely defined in many countries. This study was performed to gain a greater understanding of the non-clinical determinants of prognosis of PLHIV in Myanmar.

methodsSelected demographic, behavioural and socioeconomic characteristics of outpatients at two specialist HIV hospitals and one general hospital in Yangon, Myanmar were correlated with their subsequent clinical course; a poor outcome was defined as death, hospitalisation, loss to follow-up or a detectable viral load at 6 months of follow-up.

results221 consecutive individuals with advanced HIV commencing anti-retroviral therapy (ART) were enrolled in the study; their median CD4 T-cell count was 92 (44-158) cells/mm

conclusionsMen starting ART in Myanmar have a poorer prognosis than women. Expanded implementation of gender-specific management strategies is likely to be necessary to improve outcomes.

Indexed as

HIV InfectionsSocial Determinants of HealthCD4 Lymphocyte CountCohort StudiesFemaleHumansMaleMyanmarViral LoadAcquired immunodeficiency syndromeGenderHIVMyanmarSocial determinants of health

Identifiers

PMID34372879
PMCPMC8350926

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.