ArticleBMC musculoskeletal disorders2021
Prediction and trend of tactile acuity, pain and disability in acute LBP: a six-month prospective cohort study.
Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- The clinical course of acute, subacute and persistent low back pain: a systematic review and meta-analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024Pooled it
- Altered somatosensory temporal discrimination in chronic non-specific low back pain patients with central sensitization-related features: a cross-sectional study.The Korean journal of pain · 2026Article
- Disrupted topological organization of brain connectome in patients with chronic low back related leg pain and clinical correlations.Scientific reports · 2025Article
- Inter- and Intra-Examiner Reliability Study of Two-Point Discrimination Test (TPD) and Two-Point Estimation Task (TPE) in the Sacral Area of Pain-Free Individuals.Diagnostics (Basel, Switzerland) · 2023Article
- Tactile acuity improves during acute experimental pain of the limb.Pain reports · 2023Article
- Spatial Tuning in Nociceptive Processing Is Driven by Attention.The journal of pain · 2023Article
- Adaptive changes in sensorimotor processing in patients with acute low back pain.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic back pain is known to be associated with altered tactile acuity. Tactile acuity is measured using the Two-Point Discrimination (TPD) test in both clinical and research settings. In subjects with chronic low back pain, the TPD threshold (TPDT) is increased and is associated with persistent pain. It remains unknown, however, whether TPDT is also altered in cases of clinical acute pain, or whether it could be used as a predictor of future pain and disability at an early stage of LBP. The main objective of this study was to investigate the predictive value of baseline TPDT for pain and disability at 3 and 6 months after the onset of acute LBP. The TPDT in acute low back pain (LBP) and the development of TPDT over 6 months has also been assessed.
methodsLBP participants (n = 124) with acute LBP (< 4 weeks) were included. Subjects were examined within 4 weeks of pain onset and followed-up after 3 and 6 months of pain onset. Horizontal and vertical TPDTs of the lower back were collected. Linear mixed models were subsequently used to evaluate the association of TPDT with pain and disability over time.
resultsThe vertical TPDT showed a mean (SD) of 4.9 cm (1.6) and the horizontal TPDT a mean (SD) of 6.0 cm (1.5) at baseline. The vertical TPDT altered from baseline up to 6 months from 4.9 to 4.6 cm and the horizontal TPDT from 6.0 to 5.4 cm. The association between the TPDT and the Oswestry Disability Index (ODI) after 6 months was moderate. Linear mixed models revealed no association between TPDT, pain and disability over the progression of LBP.
conclusionTPDTs appear to be raised in subjects with acute LBP. However, our study revealed no predictive capability of the TPDT for disability and pain. No comparisons are possible in the absence of similar studies, indicating the need for further research is in this area.
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