ArticleBMC cardiovascular disorders2021
Non-specific pain and 30-day readmission in acute coronary syndromes: findings from the TRACE-CORE prospective cohort.
Article in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- Rationale and Design of a Randomised Proof-of-Concept Trial to Assess the Safety of Early Discharge Using Index Microcirculatory Resistance in Patients with Acute Myocardial Infarction: SECURE Study.Journal of personalized medicine · 2026Article
- Development and Temporal Validation of a Logistic Regression-Based Risk Score for Identifying Life-Threatening Chest Pain at Emergency Department Triage: A Retrospective Cohort Study.Vascular health and risk management · 2026Observational
- Evaluating the potential of the outcome-oriented nursing assessment for acute care (ePA-AC) to identify cardiovascular patients at risk for unplanned 30- and 180-day all-cause readmission: Development and validation of a routine data-based model.American heart journal plus : cardiology research and practice · 2025Article
- One-year unplanned readmission after percutaneous coronary intervention in ST-elevation myocardial infarction: rates, causes, and predictors-a retrospective cohort study.Frontiers in cardiovascular medicine · 2025Article
- Facilitators and barriers to post-discharge pain assessment and triage: a qualitative study of nurses' and patients' perspectives.BMC health services research · 2021Article
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Authors and funding
7 authors at 3 institutions in 1 country.
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Abstract
backgroundPatients with acute coronary syndromes often experience non-specific (generic) pain after hospital discharge. However, evidence about the association between post-discharge non-specific pain and rehospitalization remains limited.
methodsWe analyzed data from the Transitions, Risks, and Actions in Coronary Events Center for Outcomes Research and Education (TRACE-CORE) prospective cohort. TRACE-CORE followed patients with acute coronary syndromes for 24 months post-discharge from the index hospitalization, collected patient-reported generic pain (using SF-36) and chest pain (using the Seattle Angina Questionnaire) and rehospitalization events. We assessed the association between generic pain and 30-day rehospitalization using multivariable logistic regression (N = 787). We also examined the associations among patient-reported pain, pain documentation identified by natural language processing (NLP) from electronic health record (EHR) notes, and the outcome.
resultsPatients were 62 years old (SD = 11.4), with 5.1% Black or Hispanic individuals and 29.9% women. Within 30 days post-discharge, 87 (11.1%) patients were re-hospitalized. Patient-reported mild-to-moderate pain, without EHR documentation, was associated with 30-day rehospitalization (odds ratio [OR]: 2.03, 95% confidence interval [CI]: 1.14-3.62, reference: no pain) after adjusting for baseline characteristics; while patient-reported mild-to-moderate pain with EHR documentation (presumably addressed) was not (OR: 1.23, 95% CI: 0.52-2.90). Severe pain was also associated with 30-day rehospitalization (OR: 3.16, 95% CI: 1.32-7.54), even after further adjusting for chest pain (OR: 2.59, 95% CI: 1.06-6.35).
conclusionsPatient-reported post-discharge generic pain was positively associated with 30-day rehospitalization. Future studies should further disentangle the impact of cardiac and non-cardiac pain on rehospitalization and develop strategies to support the timely management of post-discharge pain by healthcare providers.
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