ArticleBMC infectious diseases2021
"OPTIONS-DC", a feasible discharge planning conference to expand infection treatment options for people with substance use disorder.
Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 36 citations in OpenAlex.
- Patient-Directed Discharge Among Hospitalized Persons With Opioid Use Disorder in the Fentanyl Era: A Scoping Review.American journal of medicine open · 2026Review
- 2026 Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK.JAC-antimicrobial resistance · 2026Review
- Bacterial and fungal infections in persons who inject drugs.Clinical microbiology reviews · 2025Review
- OPTIONS-DC: Treatment Course Outcomes Following Outpatient Parenteral Antimicrobial Therapy RN-Led Multidisciplinary Care Conferences for People Who Use Drugs Hospitalized With Complex Infections.Open forum infectious diseases · 2025Article
- Management of People Who Inject Drugs With Serious Injection-Related Infections in an Outpatient Setting: A Scoping Review.Open forum infectious diseases · 2024Article
- PICC Your Poison: Resident Beliefs and Attitudes Regarding Discharge Parenteral Antibiotics for Patients Who Inject Drugs.Open forum infectious diseases · 2024Article
- Frame Shift: Focusing on Harm Reduction and Shared Decision Making for People Who Use Drugs Hospitalized With Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Drug preparation, injection-related infections, and harm reduction practices among a national sample of individuals entering treatment for opioid use disorder.Harm reduction journal · 2024Article
- Harm Reduction: A Missing Piece to the Holistic Care of Patients Who Inject Drugs.Open forum infectious diseases · 2023Article
- Perspectives on the Use of Outpatient Parenteral Antibiotic Therapy for People who Inject Drugs: Results From an Online Survey of Infectious Diseases Clinicians.Open forum infectious diseases · 2023Article
- "That Line Just Kept Moving": Motivations and Experiences of People Who Use Methamphetamine.The western journal of emergency medicine · 2023Article
- Outcomes of Partial Oral Antibiotic Treatment for Complicated Staphylococcus aureus Bacteremia in People Who Inject Drugs.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Implementation of an integrated infectious disease and substance use disorder team for injection drug use-associated infections: a qualitative study.Addiction science & clinical practice · 2023Article
- Partial-Oral Antibiotic Therapy for Bone and Joint Infections in People With Recent Injection Drug Use.Open forum infectious diseases · 2023Article
- Empowering People with Substance Use Disorders to Self-Administer Intravenous Antibiotics at Home.Journal of general internal medicine · 2022Article
- A Taxonomy of Hospital-Based Addiction Care Models: a Scoping Review and Key Informant Interviews.Journal of general internal medicine · 2022Article
- A Bundle of the Top 10 OPAT Publications in 2021.Open forum infectious diseases · 2022Article
- Experiences Using a Multidisciplinary Model for Treating Injection Drug Use Associated Infections: A Qualitative Study.Frontiers in psychiatry · 2022Article
- Health Care Utilization Patterns for Patients With a History of Substance Use Requiring OPAT.Open forum infectious diseases · 2021Article
- Improving care for individuals with serious infections who inject drugs.Therapeutic advances in infectious diseaseArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSerious bacterial infections associated with substance use often result in long hospitalizations, premature discharges, and high costs. Out-of-hospital treatment options in people with substance use disorder (SUD) are often limited.
methodsWe describe a novel multidisciplinary and interprofessional care conference, "OPTIONS-DC," to identify treatment options agreeable to both patients and providers using the frameworks of harm reduction and patient-centered care. We retrospectively reviewed charts of patients who had an OPTIONS-DC between February 2018 and July 2019 and used content analysis to understand the conferences' effects on antibiotic treatment options.
resultsFifty patients had an OPTIONS-DC during the study window. Forty-two (84%) had some intravenous (IV) substance use and 44 (88%) had an active substance use disorder. Participants' primary substances included opioids (65%) or methamphetamines (28%). On average, conferences lasted 28 min. OPTIONS-DC providers recommended out-of-hospital antibiotic treatment options for 34 (68%) of patients. OPTIONS-DC recommended first line therapy of IV antibiotics for 35 (70%) patients, long-acting injectable antibiotics for 14 (28%), and oral therapy for 1 (2%). 35 (70%) patients that had an OPTIONS-DC completed an antibiotic course and 6 (12%) left the hospital prematurely. OPTIONS-DC expanded treatment options by exposing and contextualizing SUD, psychosocial risk and protective factors; incorporating patient preferences; and allowing providers to tailor antibiotic and SUD recommendations.
conclusionsOPTIONS-DC is a feasible intervention that allows providers to integrate principles of harm reduction and offer patient-centered choices among patients needing prolonged antibiotic treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.