Evidence map›Paper›PMID 34372703›Full record

ArticlemBio2021

O-Specific Antigen-Dependent Surface Hydrophobicity Mediates Aggregate Assembly Type in Pseudomonas aeruginosa.

Sheyda Azimi, Jacob Thomas, Sara E Cleland, Jennifer E Curtis, Joanna B Goldberg, Stephen P Diggle

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 citations in OpenAlex.

  1. Morphogenesis of bacterial colonies in liquid crystalline environments.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  3. Biophysical Constraints Dictate the Stability of Social Traits inbioRxiv : the preprint server for biology · 2026
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  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Biofilm Formation ofMicroorganisms · 2025
    Review
  12. Article
  13. A rhamnose-rich O-antigen ofJournal of bacteriology · 2025
    Article
  14. Exploring aggregation genes in aJournal of bacteriology · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Antibiotics (Basel, Switzerland) · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sheyda AzimiCenter for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technologygrid.213917.f, Atlanta, Georgia, USA.
Jacob ThomasCenter for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technologygrid.213917.f, Atlanta, Georgia, USA.
Sara E ClelandCenter for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technologygrid.213917.f, Atlanta, Georgia, USA.
Jennifer E CurtisSchool of Physics, Georgia Institute of Technologygrid.213917.f, Atlanta, Georgia, USA.
Joanna B GoldbergDivision of Pulmonology, Allergy/Immunology, Cystic Fibrosis and Sleep, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Stephen P DiggleCenter for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technologygrid.213917.f, Atlanta, Georgia, USA.
Georgia Institute of Technology · USEmory University · US

Funding

Understanding in vivo antibiotic resistance in diverse Pseudomonas aeruginosa populationsR01AI153116 · NIAID · GEORGIA INSTITUTE OF TECHNOLOGY · PI DIGGLE, STEPHEN PAUL · 2021 to 2025
$2.3M
Understanding in vivo antibiotic resistance in diverse Pseudomonas aeruginosa populationsR56AI153116 · NIAID · GEORGIA INSTITUTE OF TECHNOLOGY · PI DIGGLE, STEPHEN PAUL · 2020 to 2020
$508k
NIAID NIH HHS R01 AI153116NIAID NIH HHS R56 AI153116
6 · The paper itself

Abstract

Bacteria live in spatially organized aggregates during chronic infections, where they adapt to the host environment, evade immune responses, and resist therapeutic interventions. Although it is known that environmental factors such as polymers influence bacterial aggregation, it is not clear how bacterial adaptation during chronic infection impacts the formation and spatial organization of aggregates in the presence of polymers. Here, we show that in an

Indexed as

Hydrophobic and Hydrophilic InteractionsBiofilmsCystic FibrosisDNAHumansIn Vitro TechniquesMucinsO AntigensPolymersPseudomonas aeruginosaDNAMucinsO AntigensPolymerscystic fibrosisdepletion aggregationhydrophobicitylipopolysaccharideO-antigenPseudomonas aeruginosa

Identifiers

PMID34372703
PMCPMC8406328
OpenAlexW3120104994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.