Evidence map›Paper›PMID 34372618›Full record

ArticleViruses2021

Seroprevalence of SARS-CoV-2 Binding and Neutralizing Antibodies in Healthcare Workers during the Epidemic Peak in Referral Hospitals and Quarantine Sites: Saudi Arabia.

Rowa Y Alhabbab, Ahdab Alsaieedi, Abdullah Algaissi, Sara Almahboub, Rajaa M Al-Raddadi, Omaima I Shabouni, Rahaf Alhabbab, Abdulelah A Alfaraj, Sawsan S Alamri, Najwa D Aljehani and 7 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 1 country.

Rowa Y AlhabbabVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Ahdab AlsaieediVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Abdullah AlgaissiDepartment of Medical Laboratories Technology, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-5386-406X
Sara AlmahboubVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Rajaa M Al-RaddadiDepartment of Community Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Omaima I ShabouniMinistry of Health, Jeddah 23325, Saudi Arabia.ORCID 0000-0002-7020-4143
Rahaf AlhabbabDepartment of Oral and Maxillofacial Surgery, King Fahad General Hospital, Jeddah 23325, Saudi Arabia.
Abdulelah A AlfarajDepartment of Phlebotomy, Blood Bank & Laboratory, King Fahad General Hospital, Jeddah 23325, Saudi Arabia.
Sawsan S AlamriVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Najwa D AljehaniVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Rwaa H AbdulalVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Mohamed A AlfalehVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-3716-0019
Turki S AbujamelVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Almohanad A AlkayyalDepartment of Medical Laboratory Technology, University of Tabuk, Tabuk 71491, Saudi Arabia.
Ahmad Bakur MahmoudCollege of Applied Medical Sciences, Taibah University, Almadinah Almunwarah 42353, Saudi Arabia.
Adel M AbuzenadahDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Anwar M HashemVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-8471-7011
King Abdulaziz University · SAJazan University · SAKing Fahad Hospital Jeddah · SAMinistry of Health · SATaibah University · SAUniversity of Tabuk · SA

Funding

King Abdulaziz University GCV19-45-1441
6 · The paper itself

Abstract

Healthcare workers (HCWs) are at high risk for SARS-CoV-2 infection compared to the general population. Here, we aimed to evaluate and characterize the SARS-CoV-2 seropositivity rate in randomly collected samples among HCWs from the largest referral hospitals and quarantine sites during the peak of the COVID-19 epidemic in the city of Jeddah, the second largest city in Saudi Arabia, using a cross-sectional analytic study design. Out of 693 participants recruited from 29 June to 10 August 2020, 223 (32.2%, 95% CI: 28.8-35.8) were found to be confirmed seropositive for SARS-CoV-2 antibodies, and among those 197 (88.3%) had never been diagnosed with COVID-19. Seropositivity was not significantly associated with participants reporting COVID-19 compatible symptoms as most seropositive HCW participants 140 (62.8%) were asymptomatic. The large proportion of asymptomatic SARS-CoV-2 cases detected in our study demands periodic testing as a general hospital policy.

Indexed as

AdultAnimalsAntibodies, NeutralizingAntibodies, ViralAsymptomatic InfectionsChlorocebus aethiopsCOVID-19COVID-19 Serological TestingCross-Sectional StudiesFemaleHealth PersonnelHumansInfection ControlMaleMiddle AgedQuarantineAntibodies, NeutralizingAntibodies, Viralanti-S AbsCOVID-19 pandemicHCWsJeddahSARS-CoV-2seroprevalence

Identifiers

PMID34372618
PMCPMC8310370
OpenAlexW3185636691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.