Evidence map›Paper›PMID 34372614›Full record

ReviewViruses2021

Oncolytic HSV: Underpinnings of Tumor Susceptibility.

Chase Kangas, Eric Krawczyk, Bin He

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Oncolytic human herpesvirus for cancer therapy.Molecular biology reports · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chase KangasDepartment of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.
Eric KrawczykDepartment of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.
Bin HeDepartment of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.ORCID 0000-0001-7385-5542
University of Illinois Urbana-Champaign · US

Funding

Viral determinants in HSV virulenceR01AI148148 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI HE, BIN · 2020 to 2024
$2.4M
Breast cancer virotherapyR21CA252027 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI HE, BIN · 2021 to 2022
$407k
NCI NIH HHS R21 CA252027NIAID NIH HHS R01 AI148148
6 · The paper itself

Abstract

Oncolytic herpes simplex virus (oHSV) is a therapeutic modality that has seen substantial success for the treatment of cancer, though much remains to be improved. Commonly attenuated through the deletion or alteration of the γ

Indexed as

AnimalsCytokinesHerpesvirus 1, HumanHost Microbial InteractionsHumansMiceOncolytic VirotherapyOncolytic VirusesCytokinesherpes simplex virusimmunotherapyinterferononcolytic virusSTINGT-VECvirotherapy

Identifiers

PMID34372614
PMCPMC8310378
OpenAlexW3185231759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.