Evidence map›Paper›PMID 34372494›Full record

ReviewViruses2021

Lentiviral Vectors for Delivery of Gene-Editing Systems Based on CRISPR/Cas: Current State and Perspectives.

Wendy Dong, Boris Kantor

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 132 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. In Vivo T-Cell Engineering: Revolution in Delivery Strategies and Clinical Translation.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
  6. CRISPR and the Future of Cardiac Disease Therapy: A New Genetic Frontier.International journal of molecular sciences · 2026
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. The Role of CRISPR and Its Therapeutic Applications in Glioblastoma.International journal of molecular sciences · 2026
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. CAR-T Cell Therapy for Central Nervous System Tumors.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  18. Review
  19. International journal of biological sciences · 2026
    Review
  20. Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wendy DongDepartment of Neurobiology, Duke University Medical Center, Duke University, DUMC Box 3209, Durham, NC 27710, USA.
Boris KantorDepartment of Neurobiology, Duke University Medical Center, Duke University, DUMC Box 3209, Durham, NC 27710, USA.ORCID 0000-0002-8347-7992
Duke University · US

Funding

Control of Cocaine Seeking by D1-dependent Modulation of NMDA SignalingK01DA031747 · NIDA · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ORTINSKI, PAVEL IVANOVICH · 2012 to 2016
$696k
NIDA NIH HHS K01 DA031747
6 · The paper itself

Abstract

CRISPR/Cas technology has revolutionized the fields of the genome- and epigenome-editing by supplying unparalleled control over genomic sequences and expression. Lentiviral vector (LV) systems are one of the main delivery vehicles for the CRISPR/Cas systems due to (

Indexed as

Genetic VectorsAnimalsCRISPR-Associated Protein 9CRISPR-Cas SystemsGene EditingHumansIntegrasesLentivirusMiceTransgenesCRISPR-Associated Protein 9Integrasesbase-editingCRISPR/Cas9 systemsepigenome-editinggene therapygenome-editingintergrase-deficient lentiviral vectorslentiviral vectorsprime-editingvector mediated gene-to-cell transfer

Identifiers

PMID34372494
PMCPMC8310029
OpenAlexW3176314140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.